In vitro translation of in vivo stimulation

加拿大被称为国际领导者，大学、行业和机构的研究人员之间的合作努力有着悠久的历史。尽管胚胎生产在几十年内是可行的，但产量仍然不是最理想的，特别是当卵母细胞来自小卵泡直径时。即使卵泡的生长需要几个月的时间，获得发育能力的关键事件发生在卵泡的最终成熟前后，这一步骤发生在排卵之前。改善这种能力的策略之一是通过卵泡晚期信号影响卵母细胞，同时卵母细胞保持在减数分裂停滞状态，因为它发生在卵泡环境中。我们最近开发了所谓的“Stop-Egg-Go”作为一种生理处理方法，以有效地维持牛卵母细胞在减数分裂停滞中的状态。这种方法具有很高的商业意义，因为它为提高卵母细胞的发育能力提供了一个关键的窗口。此外，它还将允许将卵母细胞运送到实验室，这是扩大奶牛繁殖技术市场的关键替代方案。

Known as an international leader, Canada has a long history of collaborative efforts between researchers from universities, industries and agencies. In spite of embryonic production is feasible for several decades; the yield is still not optimal especially when oocytes are from small follicular diameters. Even if several months are required for the growth of the ovarian follicles, the crucial events for developmental competence acquisition are occurring around the final maturation of the follicles, a step happening before ovulation. One of the proposed strategies to improve this competence is to influence the oocyte with the late follicular signalling while the oocyte is maintained in meiotic arrest as it occurs naturally in the follicular environment. We have recently developed the so-called "Stop-Egg-Go" as a physiological treatment to efficiently maintain bovine oocytes in meiotic arrest. This approach is of high commercial relevance since it provides a critical window to improve developmental competence of oocytes. In addition, it will allow the transport of oocytes to the laboratory, a key alternative for the expansion of reproductive technologies in dairy cow market.