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Synthetic NOD-like receptor ligands for modulating immune responses

Synthetic NOD-like receptor ligands for modulating immune responses
用于调节免疫反应的合成 NOD 样受体配体
批准号:
469917-2014
负责人:
Jiang, ZiHua
金额:
$1.82万
依托单位:
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31

项目摘要

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中文摘要
翻译
细菌对抗生素的耐药性上升已经成为一个世界性的问题。据估计,在许多发达国家,家畜消耗了50-80%的抗生素,这些抗生素不仅用于治疗活动性感染,而且还用于预防感染。为了减少农场动物抗生素的使用,我们需要提高目前控制农场动物感染的方法的功效。增强牲畜的免疫系统将使这些动物更好地对抗各种感染。
英文摘要
The rise of bacterial resistance to antibiotics has become a worldwide problem. In many developed countries, it is estimated that livestock consume 50-80% of antibiotics which are used not only to treat active infections but also prophylactically to prevent infections. In order to reduce the use of antibiotics in farm animals, we need to improve the efficacy of currently existing methods to control infections in farm animals. Boosting the immune system of livestock will allow these animals to better fight against various infections.
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会议论文
Modulation of Innate Immune Responses: Synthesis and Biological Studies of Homo- and Hetero-dimeric Pattern Recognition Receptor Agonists and Other Immunostimulants
  • 批准号:
    RGPIN-2017-05363
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.6万
  • 财政年份:
    2022
  • 负责人:
    Jiang, ZiHua
  • 依托单位:
Modulation of Innate Immune Responses: Synthesis and Biological Studies of Homo- and Hetero-dimeric Pattern Recognition Receptor Agonists and Other Immunostimulants
  • 批准号:
    RGPIN-2017-05363
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.6万
  • 财政年份:
    2020
  • 负责人:
    Jiang, ZiHua
  • 依托单位:
Modulation of Innate Immune Responses: Synthesis and Biological Studies of Homo- and Hetero-dimeric Pattern Recognition Receptor Agonists and Other Immunostimulants
  • 批准号:
    RGPIN-2017-05363
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.6万
  • 财政年份:
    2019
  • 负责人:
    Jiang, ZiHua
  • 依托单位:
Modulation of Innate Immune Responses: Synthesis and Biological Studies of Homo- and Hetero-dimeric Pattern Recognition Receptor Agonists and Other Immunostimulants
  • 批准号:
    RGPIN-2017-05363
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.6万
  • 财政年份:
    2018
  • 负责人:
    Jiang, ZiHua
  • 依托单位:
国内基金
海外基金
NOD1泛素化介导CD8⁺T细胞调控子宫内膜癌免疫逃逸的机制研究
VCPIP1介导Erbin去泛素化调节NOD2/RICK依赖的巨噬细胞自噬在脓毒症中的作用及机制研究
  • 批准号:
    JCZRLH202600698
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
  • 依托单位:
基于NOD样受体信号通路探讨芪术石斛养胃方逆转慢性萎缩性胃炎癌前病变的机制
木香烃内酯靶向抑制NOD1/2逆转肿瘤治疗抵抗的作用及机制研究
  • 批准号:
    QN25H310005
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    韦细端
  • 依托单位: