Development of a metallurgical Canadian platform for the processing of added-value materials and semi-finished products for the global medical industry

本提案的目的是为全球医疗工业开发一个加拿大冶金平台，用于加工增值材料和半成品。重点是解决ß-Ti合金制造半成品医疗产品。主要针对心血管应用。用于医疗产品和保健产品的钛合金具有重量轻、机械性能高和无可争议的生物相容性，是一种有价值的替代品。通过实验室经验和模拟，获得了机械性能的初步模式，并对其进行了优化。此外，心血管装置需要特定的表面改性和高质量的生产标准，因此将开发一种综合方法。设计，优化，以及半成品的测试将被解决。这需要大量的高科技、人力和时间。在这个项目中，将由拉瓦尔大学的生物材料和生物工程实验室和三河流域的quacimtallurgie du quacimtallurgie du quacimul中心的互补专业知识组成一个特殊和熟练的小组。前者将带来医疗器械生物材料领域超过15年的学术和工业专业知识，而后者将以真正的技术转移为导向的方式，为该项目注入生产ß-钛合金（作为基础材料）和半成品所需的彻底的科学和技术环境。四家高度互补和值得信赖的公司将提供来自其核心业务的直接专业知识，以及与实际生产过程相关的材料、技术、服务和知识反馈。这种深度交流将有利于高素质人才的教育，使他们接触到高科技环境，并有机会开发知识产权，并成为该项目（已经设想的）下一步发展的一部分。如果这个项目成功，加拿大将有可能成为世界上为数不多的为下一代心血管设备提供新型先进材料和半成品的供应商之一。

The present proposal is aimed to develop a metallurgical Canadian platform for the processing of added-value materials and semi-finished products for the Global medical industry. The focus is addressed over ß-Ti alloys to fabricate semi-finished medical products. Cardiovascular applications are mainly targeted. Titanium alloys for medical products and healthcare goods represents a valuable alternative for their low weight, high mechanical properties and uncontested biocompatibility. A preliminary pattern of the mechanical properties will be obtained and successively optimised by laboratory experiences and simulations. In addition, cardiovascular devices need specific surface modification and high quality production standards, so that an integrated approach will be developed. The design, the optimization, as well as testing of semi-finished products will be addressed. This requires plenty of high technology, personnel and time. In this project, an exceptional and skilled team will be constituted by the complementary expertise of Laboratory for Biomaterials and Bioengineering at Université Laval and Centre de Métallurgie du Québec, in Trois-Rivières. The first will bring more than 15 years of academic and industrial expertise in the field of biomaterials for medical devices while the second will inject in this project the thorough scientific and technological environment required for the production of ß-Ti alloys, as base material, and semi-finished products, with a genuine technological-transfer-oriented approach. Four highly complementary and trustable companies will provide direct expertise from their core business, but also materials, technology, services and knowledge feedbacks related to factual production processes. This deep level of exchange will benefit toward the education of high quality personnel, by exposing them to a high technology environment and the chance of developing intellectual properties and be part of the (already envisaged) next development of this project. This project, if successful, presents the potential for Canada to become one of the rare world-supplier for new advanced materials and semi-finished products for the next generation of cardiovascular devices.