Understanding the surface properties of the drug delivery device and the oscillating positive expiratory pressure device

Trudell Medical International （TMI）是一家专业从事呼吸治疗设备的行业领先的医疗设备公司。他们的产品改善了加拿大和国际呼吸系统疾病患者的生活。TMI的呼吸治疗设备可以提高患者的肺功能。它们有效的家庭治疗减轻了医院的负担，总的来说，更容易让患者回归生活，为社会做贡献。这项研究旨在了解药物输送系统的表面特性，该系统的效率与药物杯中保留的液体有关。改变表面的润湿性将允许人们减少保留的液体并改善装置的给药性能。在相关区域，振荡呼气正压装置的表面

Trudell Medical International (TMI) is an industry leading medical device company that specializes in respiratory therapy devices. Their products improve the lives of patients with respiratory disease across Canada and internationally. TMI's respiratory therapy devices boost patient lung function. Their effective at-home treatments relieve the burdens imposed on hospitals and, in general, more easily allow sufferers to return to their lives and contribute to society. This Engage Grant looks at understanding surface properties of a drug delivery system whose efficiency is related to the retained liquid of its medication cup. Changing the wettability of the surface will allow one to reduce the retained liquid and improve the drug delivery performance of the device. In a related area, the surfaces of the Oscillating Positive Expiratory Pressure device encounter friction as the device is used. A thorough understanding of the chemistry and morphology of these surfaces will be ascertained by employing analytical techniques such as atomic force microscopy, X-ray photoelectron spectroscopy, scanning electron microscopy, Fourier transform infrared spectroscopy and contact angle. Based on the results from this NSERC Engage project, we will recommend solutions to the specified wettability and friction issues and look for further collaboration with the company in order to develop technologies that benefit these medical devices. TMI is a major manufacturer of medical devices that assist people with respiratory problems and resolution of these issues will provide them with a competitive advantage and benefit their customers across Canada. Our propose project is well-defined to help improved the design of these products.