Development of a metallurgical Canadian platform for the processing of added-value materials and semi-finished products for the global medical industry

本提案旨在为全球医疗行业开发一个冶金加拿大平台，用于加工增值材料和半成品。重点讨论了用于制造半成品医疗产品的钛合金。主要针对心血管应用。用于医疗产品和医疗保健产品的钛合金因其重量轻、机械性能高和无可争议的生物相容性而成为一种有价值的替代品。将获得机械性能的初步模式，并通过实验室经验和模拟进行连续优化。此外，心血管器械需要特定的表面改性和高质量的生产标准，以便开发综合方法。半成品的设计、优化和测试将得到解决。这需要大量的高技术、人员和时间。在本项目中，拉瓦尔大学生物材料和生物工程实验室和位于三河的魁北克省医学中心的互补专业知识将组成一支出色而熟练的团队。第一个项目将带来医疗器械生物材料领域超过15年的学术和工业专业知识，而第二个项目将为该项目注入生产作为基础材料的钛合金和半成品所需的全面科学和技术环境，并采用真正的技术转移导向方法。四家高度互补和值得信赖的公司将提供来自其核心业务的直接专业知识，以及与实际生产过程相关的材料，技术，服务和知识反馈。这种深层次的交流将有利于高素质人才的教育，使他们接触到高科技环境和开发知识产权的机会，并成为该项目（已经设想的）下一个发展的一部分。该项目如果成功，将使加拿大成为下一代心血管器械的新型先进材料和半成品的世界罕见供应商之一。

The present proposal is aimed to develop a metallurgical Canadian platform for the processing of added-value materials and semi-finished products for the Global medical industry. The focus is addressed over ß-Ti alloys to fabricate semi-finished medical products. Cardiovascular applications are mainly targeted. Titanium alloys for medical products and healthcare goods represents a valuable alternative for their low weight, high mechanical properties and uncontested biocompatibility. A preliminary pattern of the mechanical properties will be obtained and successively optimised by laboratory experiences and simulations. In addition, cardiovascular devices need specific surface modification and high quality production standards, so that an integrated approach will be developed. The design, the optimization, as well as testing of semi-finished products will be addressed. This requires plenty of high technology, personnel and time. In this project, an exceptional and skilled team will be constituted by the complementary expertise of Laboratory for Biomaterials and Bioengineering at Université Laval and Centre de Métallurgie du Québec, in Trois-Rivières. The first will bring more than 15 years of academic and industrial expertise in the field of biomaterials for medical devices while the second will inject in this project the thorough scientific and technological environment required for the production of ß-Ti alloys, as base material, and semi-finished products, with a genuine technological-transfer-oriented approach. Four highly complementary and trustable companies will provide direct expertise from their core business, but also materials, technology, services and knowledge feedbacks related to factual production processes. This deep level of exchange will benefit toward the education of high quality personnel, by exposing them to a high technology environment and the chance of developing intellectual properties and be part of the (already envisaged) next development of this project. This project, if successful, presents the potential for Canada to become one of the rare world-supplier for new advanced materials and semi-finished products for the next generation of cardiovascular devices.