Development of an In-House Genetic Screening Toolbox to Select and Grow Pathogen-Resistant Strains of Cannabis sativa.

LyonLeaf大麻公司是一家获得联邦政府许可的优质大麻生产商，旨在缩小住院患者对标准化医用大麻需求的差距。它致力于促进关于工业环境中大麻种植的研究，以及关于大麻产品衍生物对病人健康和福祉影响的研究。了解大麻品种对常见病原体的抗药性将有助于查明不易致病的品种，因此可能更容易商业化。La Cité学院的生物创新技术访问中心将为LyonLeaf提供知识，专业知识和能力，以评估作物中存在哪些病原体，并开发技术来选择能够在目前的病原体基因型无法茁壮成长的病原体抗性基因型。LyonLeaf和La Cité之间的这一合作研究项目将涉及常见病原体的遗传标记识别、利用分子生物学设备进行遗传分析以及通过对大麻幼苗应用和观察病原体来验证方法。在该项目结束时，LyonLeaf应该能够自主开发出对设施中的病原体具有抗性的新品种，以实现更可持续的生产，这将有助于加强他们在国内市场上的地位。

LyonLeaf Cannabis Inc. is a federally licensed producer of premium cannabis and aims to close the gap inpatients' needs for standardized medical cannabis. It is committed to contributing to the body of research oncultivation of cannabis in industrial settings, as well as research on effects of cannabis product derivatives on health and well-being of medical patients. Understanding of resistance of cannabis strains to commonpathogens will help in identifying those strains that are not prone to diseases, and therefore may be more easily commercialized. The Technology Access Centre in Bio-Innovation at College La Cité would provide LyonLeafwith the knowledge, expertise and capabilities to assess which pathogens are present in their crop and develop techniques to select pathogen resistant genotypes that will be able to thrive where the present susceptiblegenotypes do not. This collaborative research project between LyonLeaf and La Cité would involve geneticmarker identification of common pathogens, genetic analyses using molecular biology equipment, andvalidation of methodology by application and observation of pathogen to cannabis plantlets. At the end of this project, LyonLeaf should be able to autonomously develop new varieties resistant to the pathogens encounteredin their facility, toward a more sustainable production which will help strengthen their position in the national market.