Adapting the business model to rapidly produce and market efficacious hand sanitizing foam to combat and contain the COVID-19 outbreak

调整业务模式，快速生产和销售有效的洗手泡沫，以对抗和遏制 COVID-19 疫情

• 批准号: 554696-2020
• 负责人: Méthot, Nathalie
• 金额: $ 5.14万
• 依托单位: La Cité collégiale
• 依托单位国家: 加拿大
• 项目类别: Applied Research Rapid Response to COVID-19
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=696123
• 关键词: Adapting; business; model; rapidly; produce

The purpose of this project is to develop a gentle foaming hand sanitizer that shows 99.9% efficacy at destroying microorganisms that cause infections to help palliate the shortage of personal antiseptics and establish long-term suppliers to maintain accessibility. We propose to formulate a foam-based antiseptic product and test its efficacy of pathogen lethality to indicate 'kills 99.9% of germs' on the product label. Foaming hand sanitizers cling to hands better than liquid hand sanitizer and less of it is required per use. The development and production of an effective foaming hand sanitizer will provide another available option of personal antiseptic to consumers to reduce the transmission of microbes in general and help combat the COVID-19 pandemic. This project will be conducted by the Technology Access Center in Bio-Innovation at La Cité and can take place while the COVID-19 physical distancing measures are in place since controlled access to the research facilities have already been granted. Extra personal protective equipment (PPE) is given to all personnel and additional laboratory space has been made available to abide by the physical distancing recommended by the Public Health Agency of Canada. The specific aims of the project are to 1) prepare documents for research ethics approval and recruit human participants; 2) evaluate two major foam formulation types - water- vs ethanol-based - in terms of texture and gentleness on the skin; 3) test the efficiency of the foam against pathogens in vitro; and 4) evaluate the efficiency of the foam against pathogens in a clinical trial. An expert in Health Canada's regulations will be consulted during the design and performance of the trial. This proposed product would be one of the most fundamental and cost-effective ways of preventing transmission.

该项目的目的是开发一种温和的泡沫洗手液，其在破坏引起感染的微生物方面显示出99.9%的功效，以帮助缓解个人防腐剂的短缺，并建立长期供应商以保持可获得性。我们建议配制一种泡沫基抗菌产品，并测试其杀灭病原体的功效，在产品标签上注明“杀死99.9%的细菌”。泡沫洗手液比液体洗手液更容易粘手，而且每次使用所需的量更少。开发和生产有效的泡沫洗手液将为消费者提供另一种可用的个人抗菌剂选择，以减少微生物的传播，并帮助抗击COVID-19大流行。该项目将由位于La Cité的生物创新技术访问中心进行，并可在COVID-19物理距离措施实施期间进行，因为研究设施的受控访问已经获得批准。为所有人员提供了额外的个人防护设备，并提供了额外的实验室空间，以遵守加拿大公共卫生署建议的物理距离。该项目的具体目标是：1）编写研究伦理批准文件，并招募人类参与者; 2）评估两种主要的泡沫配方类型-水基与乙醇基-在质地和皮肤温和性方面; 3）测试泡沫体外对抗病原体的效率;以及4）在临床试验中评估泡沫对抗病原体的效率。在试验设计和实施期间，将咨询加拿大卫生部法规专家。这种拟议的产品将是预防传播的最基本和最具成本效益的方法之一。