Alpha-Synuclein Inoculation in Anterior Olfactory Nucleus and its Effects on Olfactory Function in Prodromal Parkinson’s Disease
Alpha-Synuclein Inoculation in Anterior Olfactory Nucleus and its Effects on Olfactory Function in Prodromal Parkinson’s Disease
批准号:
486247
负责人:
Tran Ruth
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
嗅觉低下是一种常见的非运动性症状,在帕金森氏病(PD)早期就会出现,比经典的运动性症状早至少4年。α-突触核蛋白(a-syn)是参与帕金森病发病的病理性蛋白聚集体。
英文摘要
Hyposmia, an impaired sense of smell, is a prevalent non-motor symptom that occurs early in Parkinson's Disease (PD), preceding classic motor symptoms by at least 4 years. Alpha-synuclein (a-syn), the pathological protein aggregates implicated in PD, are
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