Regulation of heterochromatin by the Retinoblastoma protein in cell cycle control and cancer

视网膜母细胞瘤蛋白在细胞周期控制和癌症中对异染色质的调节

• 批准号: 223267
• 负责人: Dick Frederick A
• 金额: $ 52.56万
• 依托单位: London Health Sciences Centre Res. Inc. (Ont.)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=223267&lang=en
• 关键词: Cell Cycle; Chromatin; Condensin; Gene-Targeted Mice; Mitosis; Senescence

Deregulated cell proliferation is one of the fundamental characteristics of cancer. In addition to unwanted cell growth, the genetic make-up of cancer cells is often unstable. This allows them to acquire new characteristics that promote increased aggres

细胞增殖失调是癌症的基本特征之一。 除了不必要的细胞生长外，癌细胞的遗传组成通常不稳定。 这使他们能够获得新的特点，促进增加聚集