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Design and Mechanistic Studies of Metal-Based Anti-Diabetic Drugs

Design and Mechanistic Studies of Metal-Based Anti-Diabetic Drugs
金属基抗糖尿病药物的设计与机理研究
批准号:
DP1095310
负责人:
Prof Peter Lay
金额:
$31.35万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-14 至 2013-12-04

项目摘要

项目成果

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中文摘要
翻译
金属补充剂,如铬和钒,因其据称的减脂和抗糖尿病活性而被广泛消费。然而,关于这些金属离子的有效性和安全性,以及它们在预防糖尿病方面是否具有重要作用,或者在某些情况下是癌症的风险因素,仍有许多需要了解。这项研究将从根本上了解这些金属络合物如何发挥抗糖尿病作用,以及如何使它们在治疗2型糖尿病方面更安全和/或更有效。2型糖尿病是一种在发达国家迅速蔓延的流行病。
英文摘要
Metal supplements, such as chromium and vanadium, are consumed widely for their purported fat reduction and anti-diabetic activities. However, much is still to be learnt about the efficacy and safety of such metal ions and whether they have an essential role in the prevention of diabetes or, in some instances, are a risk factor for cancer. The research will provide a fundamental understanding of how these metal complexes exert their anti-diabetic effects and how they can be made safer and/or more efficacious for the treatment of type 2 diabetes, which is a rapidly expanding epidemic in developed countries.
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Metal Virulence and Therapeutic Factors in Pathogen Bioinorganic Chemistry
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    DP210101632
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $42.2万
  • 财政年份:
    2021
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    Prof Peter Lay
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Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies
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  • 项目类别:
    Linkage Infrastructure, Equipment and Facilities
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  • 财政年份:
    2020
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Bioinorganic chemistry between immune cell and pathogen
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    DP180102741
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    Discovery Projects
  • 资助金额:
    $37.48万
  • 财政年份:
    2018
  • 负责人:
    Prof Peter Lay
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Roles of Metal Complexes in Carbohydrate Metabolism – Anti-Diabetic Drugs
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    DP160104172
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2016
  • 负责人:
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  • 依托单位:
海外基金