Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies

通过红外和拉曼显微镜进行快速分子（生物）材料成像

• 批准号: LE200100043
• 负责人: Prof Peter Lay
• 金额: $ 25.94万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-05-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE200100043
• 关键词: Rapid; Molecular; Bio; material; Imaging

This project aims to undertake fast probe-free biochemical/chemical imaging of heterogeneity within cells and materials surfaces with new infrared and Raman imaging. It will generate new fundamental knowledge on: cell heterogeneity and dynamic processes; technologies for optimising cell printing; understanding toxicity of microplastics; and protocols for measuring materials of technological relevance. Expected outcomes include: interdisciplinary collaborations in new protocols for in-vitro drug development; cell printing technologies; environmental impacts of microplastics; and materials design. Expected benefits include innovative approaches to early stage drug design; improved environmental controls and advances in innovative materials.

该项目旨在利用新的红外和拉曼成像技术，对细胞和材料表面的异质性进行快速、无探针的生化/化学成像。它将在以下方面产生新的基础知识：细胞异质性和动态过程；优化细胞打印的技术；了解微塑料的毒性；以及与技术相关的材料测量协议。预期成果包括：在体外药物开发新方案方面的跨学科合作；细胞打印技术；微塑料的环境影响；以及材料设计。预期的好处包括早期药物设计的创新方法；环境控制的改善和创新材料的进步。