Ion Trap and Hybrid Mass Spectrometry: Instrumentation and Applications

离子阱和混合质谱：仪器和应用

• 批准号: 8721768
• 负责人: Robert Cooks
• 金额: $ 107.75万
• 依托单位: Purdue Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-04-15 至 1994-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8721768&HistoricalAwards=false
• 关键词: Ion; Trap; Hybrid; Mass; Spectrometry

This project is in the general area of analytical and surface chemistry and in the subfields of mass spectrometry and surface science. The unifying theme of this broad experimental thrust is the development of new mass spectrometry instrumentation and its exploitation in the solution of challenging problems in trace analysis and materials characterization. Two related subareas are being addressed in this project. One focusses on the study of the interactions of low energy ions with surfaces. It seeks to detail the charge transfer, dissociation, and reaction phenomena that occur when relatively low energy monatomic and polyatomic ions strike the surfaces of metals and molecular solids. In order to carry out these studies, Professor Cooks and his students are building a new hybrid mass spectrometer that enables mass, angle, and kinetic energy selection of both reactant and product ions involved in these surface processes. This instrument also permits investigation of the chemical modification of surfaces by low energy ion deposition and high energy ion impact. The second subarea focusses on the development, characterization, and application of two other new mass spectrometry instruments, an ion trap mass spectrometer and a hybrid magnet and electric sector machine. With these two instruments, collision-activated dissociation, photoionization, photodissociation, and ion-molecule reaction techniques will be used to study phenomena of remote site fragmentation, thermodynamic vs kinetic control of gas phase dissociation processes, the use of doubly charges ions as chemical ionization reagents, the role of excited electronic states in the dissociation of small perfluorinated ions, and the formation of and reaction chemistry of energetic hypervalent species. This research will lead to the development of new mass spectrometric instrumentation and to improved, sensitive methods of chemical characterization. Additionally, this work should give rise to the continued reassertion of U.S. technology in the area of mass spectrometry. This is of particular interest at present inasmuch as the leading commercial firms in the mass spectrometry world market are currently in the United Kingdom and in Japan. It is expected that the efficient transfer of technology from the laboratories of Professor Cooks and other NSF grantees to U.S. manufacturers could significantly alter this picture in the next few years.

这个项目是在一般地区的分析和表面 化学和质谱和表面分析的子领域 科学 这个广泛的实验主旨的统一主题是 新型质谱仪器的发展及其 在解决跟踪中的挑战性问题方面的开发 分析和材料表征。 两个相关的子区域是 在这个项目中得到解决。 一个集中在研究 低能量离子与表面的相互作用。 它试图详细说明 电荷转移、离解和反应现象， 当相对低能量的单原子和多原子离子 撞击金属和分子固体的表面。为了 进行这些研究，库克教授和他的学生是 建立一个新的混合质谱仪，使质量，角度， 以及反应物和产物离子的动能选择 参与这些表面过程。 该工具还允许 表面化学改性的研究 能量离子沉积和高能离子撞击。 第二 分区域侧重于开发，表征， 应用另外两种新的质谱仪器，离子 阱质谱仪和混合磁电部分 机 有了这两个仪器，碰撞激活 解离、光电离、光解离和离子-分子 反应技术将用于研究远程站点的现象 裂解，气相的热力学与动力学控制 解离过程，使用双电荷离子作为化学物质， 电离试剂，激发电子态的作用， 小的全氟离子的解离，以及 以及高能超价物质的反应化学。 这项研究将导致开发新的质量 光谱仪器和改进的灵敏方法 的化学特征。 此外，这项工作还应 美国技术在该地区的持续重申 质谱分析的一部分。 这是目前特别感兴趣的 由于质谱分析领域的领先商业公司 世界市场目前在英国和日本。 它 预计，从技术转让的效率， Cooks教授和其他NSF资助者的实验室 制造商可能会在未来一段时间内显著改变这一局面。 几年