Acquisition of a Fourier-transform NMR Spectrometer

购买傅里叶变换核磁共振波谱仪

• 批准号: 8801786
• 负责人: Thomas Engel
• 金额: $ 22万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-08-01 至 1990-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8801786&HistoricalAwards=false
• 关键词: Acquisition; Fourier; transform; NMR; Spectrometer

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists who are carrying out frontier research. This award from the Chemistry Shared Instrumentation Program will help the Department of Chemistry at the University of Washington to acquire a high-field NMR spectrometer. Among the areas of chemical research that will be enhanced by the acquisition are included the following: 1) Conformational analysis and biorecognition phenomena 2) Synthesis and study of theoretically interesting molecules 3) Transition metal complexes with bridging nitride ligands 4) Bioorganic chemistry of natural products 5) Rational design of enzyme inhibitors 6) Organic synthesis and bioorganic chemistry 7) Oxo-organometallic chemistry.

核磁共振 (NMR) 光谱是化学家阐明分子结构的最强大工具。 它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 获得最先进的核磁共振波谱对于进行前沿研究的化学家来说至关重要。 化学共享仪器计划的这一奖项将帮助华盛顿大学化学系购买一台高场核磁共振波谱仪。 此次收购将增强的化学研究领域包括： 1) 构象分析和生物识别现象 2) 理论上有趣的分子的合成和研究 3) 具有桥接氮化物配体的过渡金属配合物 4) 天然产物的生物有机化学 5) 酶抑制剂的合理设计 6) 有机合成和生物有机化学 7) 氧化有机金属化学。