Acquisition of a 400 MHz Superconducting Nuclear Magnetic Resonance Spectrometer

佐治亚大学(UGA)化学科学学院(SES)请求提供支持，以获得核磁共振光谱仪。本文介绍了南科院六个成员的研究计划。这些计划涉及以下化学和生物化学领域：1.参与铁代谢和电子转移的新金属蛋白的表征，2.复杂生物碱和其他天然产物的结构鉴定，3.小肽的构象分析，4.酶催化反应的物理和化学机理研究。由于佐治亚大学缺乏易于获得的现代核磁共振仪器，这些计划现在受挫。核磁共振光谱仪将与其他多用户分析仪器一起放置在由SCS维护的现代集中式“仪器设施”中。

The School of Chemical Sciences (SES) at the University of Georgia (UGA) requests support to obtain a nuclear magnetic resonance spectrometer. The research programs of six members of the SCS are described here. These programs involve the following areas of Chemistry and Biochemistry: 1. Characterization of new metalloproteins involved in iron metabolism and electron transfer, 2. Structural elucidation of complex alkaloids and other natural products, 3. Conformational analysis of small peptides, 4. The study of the physical and chemical mechanisms of enzyme catalyzed reactions. These programs are now frustrated by the lack of readily accessible modern NMR instrumentation at the University of Georgia. The NMR spectrometer will be located along with other multi-user analytical instrumentation in a modern centralized "Instrument Facility" maintained by the SCS.