Microelectronic Biosensor for Neural Tissue Data Collection

这个项目是一名电气工程师和一名神经学家共同努力的结果，目的是开发一种新的传感器，使我们研究活的人脑组织及其工作原理的能力提高一个数量级。最终目标是开发一种0.3厘米乘0.3厘米的芯片，它包含16,000个独立电极，能够从脑细胞中独立记录。这项研究的另一个部分是开发技术，使脑片在与传感器接触时保持存活和功能，并设计一种在那种环境中不会恶化的传感器。测试将在已经作为手术矫正癫痫的副产品的脑片上进行；传感器数据将被分析，以了解正常组织和导致癫痫的组织之间的模式如何变化，以便深入了解大脑的正常和异常功能。

This project is a collaborative effort between an electrical engineer and a neuroscientist, to develop a new sensor capable of an order of magnitude improvement in our ability to study living human brain tissue and how it works. The ultimate goal is the development of a chip, .3 cm by .3 cm, containing 16,000 independent electrodes capable of independent recording from brain cells. Another part of the research is the development of techniques to keep brain slices alive and functional in contact with the sensor, and to design a sensor which does not deteriorate in that environment. Tests will be done on brain slices already available as a byproduct of surgery to correct epilepsy; sensor data will be analyzed to see how patterns vary between normal tissue and tissue causing the epilepsy, in order to yield insight into normal and abnormal functioning of the brain.