Cell Cycle Regulation and Differentiation in Marine Phytoplankton and Bacteria

奇泽姆博士将研究 海洋浮游生物的生长规律和动态 波动的环境是典型的海洋制度。 这种理解对于建模和设计至关重要 海洋生产力和食物网动态研究。 具体而言，它们将： * 研究硅藻的生命周期，以更好地了解 环境和遗传因素控制着从 无性生殖到有性生殖; * 研究蓝藻和海洋中的细胞周期 为了更好地了解它们的DNA循环， 在不断变化的生长条件下进行调节，以及为什么 的循环偏离了经典的E. coli模型; * 开发多渠道、高灵敏度（相对 廉价）流式细胞仪，这将有助于研究 微型浮游生物和海洋细菌。 这项工作的结果将增加我们对 海洋微生物增长率和浮游植物种群 遗传学;它也应该有助于方法的进步， 对海洋细菌的研究。 此外，它可以增强 我们对微生物生理学的基本理解， 揭示了海洋生物的特征， 经典范例

Dr. Chisholm will investigate fundamental aspects of growth regulation and dynamics of marine plankton in the fluctuating environments that are typical of oceanic regimes. This understanding is essential for modelling and designing studies of marine productivity and food web dynamics. Specifically, they will: * Study the diatom life cycle, to better understand what environmental and genetic factors control the switch from vegetative to sexual reproduction; * Investigate the cell cycle in cyanobacteria and marine bacteria, to better understand how their DNA cycle is regulated under changing growth conditions, and why aspects of the cycle deviate from the classic E. coli model; * Develop a multichannel, high-sensitivity (and relatively inexpensive) flow cytometer, which will facilitate the study small picoplankton and marine bacteria. The results of this work will augment our understanding of microbial growth rates in the sea and phytoplankton population genetics; it should also contribute methodological advances for the study of marine bacteria at sea. Moreover, it could enhance our fundamental understanding of microbial physiology by revealing features of marine organisms which deviate from classical paradigms.