Synthesis and Chemistry of New Polycyclic Systems

有了这个奖项，有机动力学项目将支持芝加哥大学化学系的菲利普·E·伊顿博士的研究。伊顿博士以合成包含特殊几何结构的分子而闻名，这些几何结构迫使构成碳的分子重新杂化并采用不寻常的成键参数。这些性质产生的系统，为键在化学反应中的作用提供了新的见解。目前的研究主要集中在六氢立方烷、1，3-脱氢立方烷、五氢立方烷、氮杂高立方烷、氮杂立方烷等高应变分子的合成。这些化合物将通过光谱学和它们的反应化学反应得到充分的表征。将使用光谱方法详细研究脱氢立方烷，以测量高度扭曲的烯烃及其卡宾异构体之间的能量差。为了确定是什么因素使这种结构比最初预测的更容易获得，正在对立方碳正离子进行研究。

With this award, the Organic Dynamics Program will support the research of Dr. Philip E. Eaton of the Department of Chemistry at the University of Chicago. Dr. Eaton is recognized for his syntheses of molecules containing special geometries that force the constituent carbons to rehybridize and adopt unusual bonding parameters. These properties produce systems which provide new insights about the role of bonding in chemical reactivity. Current studies are focused on the synthesis of hexaprismane, 1,3-dehydrocubane, pentaprismane, azahomocubanone, azacubane and other highly strained molecules. These compounds will be characterized fully by spectroscopy and by their reaction chemistry. The dehydrocubanes will be studied in detail using spectroscopic methods to measure the energy difference between a very highly twisted olefin and its carbene isomer. The cubyl carbocation is being investigated in order to determine what factors make this structure more readily accessible than originally predicted.