Acquisition of High Field NMR Spectrometer for Macromolecular Structure

获得大分子结构高场核磁共振波谱仪

• 批准号: 9015967
• 负责人: James Prestegard
• 金额: $ 35万
• 依托单位: Yale University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-03-01 至 1993-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9015967&HistoricalAwards=false
• 关键词: Acquisition; Field; NMR; Spectrometer; Macromolecular

This proposal requests funds for the purchase of a high performance, high field, instrument (500 MHz for proton observation) that will be dedicated to macromolecular structure determination. It will serve a small group of investigators in the chemistry department of Yale University who have ongoing projects directed at structure elucidation of biological macromolecules. These projects span a range of subjects that include DNA and RNA binding proteins, proteins and nucleic acids important in ribosome function, proteins important in lipid biosynthesis, and molecules important to cell surface recognition.

该提案要求资金购买专用于大分子结构测定的高性能、高场仪器（用于质子观测的 500 MHz）。 它将为耶鲁大学化学系的一小群研究人员提供服务，这些研究人员正在进行旨在阐明生物大分子结构的项目。 这些项目涵盖一系列主题，包括 DNA 和 RNA 结合蛋白、核糖体功能重要的蛋白质和核酸、脂质生物合成重要的蛋白质以及细胞表面识别重要的分子。