课题基金 / 基金详情

Identify and develop small-molecular-weight compounds for the treatment of ubiquinone deficiency and mitochondrial dysfunction.

Identify and develop small-molecular-weight compounds for the treatment of ubiquinone deficiency and mitochondrial dysfunction.
识别和开发用于治疗泛醌缺乏和线粒体功能障碍的小分子量化合物。
批准号：
379736
负责人：
Hekimi Siegfried
金额：
$50.16万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-03-01 至 2023-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=379736&lang=en
关键词：
Aging In Vivo Modes Of Delivery Of Pharmacological Compounds Micelles Mitochondrial Disease Syndrome Mode Of Action Studies Mouse Models Of Mitochondrial Dysfunction Oxidative Stress Primary And Secondary Ubiquinone Deficiency Small Molecular Weig

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中文摘要
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英文摘要
Ubiquinone, also known as Co-enzyme Q10 (CoQ10) is a natural compound found in almost all cells of all organisms, including people. It is absolutely needed for cells to function normally, in particular to be able to produce energy and to fight oxidative s
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ROS metabolism and mitochondrial function in the aging process and in age-dependent diseases.
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    McGill University
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    McGill University
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  • 负责人：
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  • 依托单位：
    McGill University