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Genetic Analysis and Metabolic Engineering of Solventogenic Clostridia

Genetic Analysis and Metabolic Engineering of Solventogenic Clostridia
产溶剂梭菌的遗传分析和代谢工程
批准号:
9210108
负责人:
Eleftherios Papoutsakis
金额:
$68.79万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1992
资助国家:
美国
项目状态:
已结题
起止时间:
1992-09-15 至 1999-02-28

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中文摘要
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英文摘要
The objectives of this project are to produce new knowledge on the molecular genetics and enzymology of anaerobic butyric clostridia that will allow beneficial genetic alterations of the cell metabolism for a variety of applications. Butyric acid clostridia have an excellent potential for industrial applications to produce commodity and specialty chemicals. The current knowledge base on the genetics, regulation and metabolism of these cells has been limited, but considerable progress has been made by work on previous grants. This project will continue the study of gene regulation, develop further the expression systems in clostridia, and evaluate other factors involved in the regulation of metabolic pathways in clostridia.
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