Purchase of X-ray Diffractometer and Computer System

化学研究仪器计划的这个奖项 将协助大学化学系 宾夕法尼亚州购买了一台X射线衍射仪， 相关的数据收集和分析系统以及升级 一台老式的X射线衍射仪 这一新工具将 大力加强若干领域的研究，包括 以下内容： 1)有机硅化合物的过渡金属配合物：新 结构和催化剂， 2)烷基硅烷催化缩合偶联成 碳硅烷， 3)天然产物的结构测定、合成及 有机光化学：Hitachimycin（a.k.a. Stubomycin），a 新的抗肿瘤剂， 4)生物有机化学：非肽模拟肽， 5)材料化学与无机催化：新型高分子材料 硼基陶瓷的前体， 6)铁电金属-氧代聚合物和金属-绝缘体 金属-氧代聚合物中的转变， 7)金属大环配合物的有机反应性， 8)抗肿瘤化合物的合成策略。 %%% 采用X射线衍射仪进行精密度和准确度测定， 一个完整的三维结构的测量， 分子。 所获得的信息给出了 给定分子的所有键距和键角， 它提供了关于空间排列的准确信息， 这个分子相对于邻近的分子。

This award from the Chemistry Research Instrumentation Program will assist the Department of Chemistry at the University of Pennsylvania in the purchase of an x-ray diffractometer and associated data collection and analysis system and an upgrade of an older x-ray diffractometer. This new instrument will enhance greatly research in a number of areas including the following: 1) Transition metal complexes of organosilicon compounds: New structures and catalysts, 2) Catalytic dehydrogenative coupling of alkylsilanes to carbosilanes, 3) Natural product structure determination, synthesis and organic photochemistry: Hitachimycin (a.k.a. Stubomycin), a novel antitumor agent, 4) Bioorganic chemistry: Non-peptidal peptidomimetics, 5) Materials chemistry and inorganic catalysis: New polymeric precursors to boron-based ceramics, 6) Ferroelectric metal-oxo polymers and metal-insulator transitions in metal-oxo polymers, 7) Organometallic reactivity of metallomacrocyclic complexes, 8) Strategies for synthesis of anti-tumor compounds. %%% The x-ray diffractometer is used to make accurate and precise measurements of the full three-dimensional structure of a molecule. The information obtained gives the precise values of all the bond distances and bond angles of a given molecule and it gives accurate information about the spatial arrangement of that molecule relative to the neighboring molecules.