Purchase of a 400 MHz NMR Spectrometer

化学研究仪器和设施计划的这一奖项将帮助特拉华大学化学系获得一台400 MHz光谱仪，该光谱仪将用于以下研究调查：G-蛋白质合成多肽类似物的结构测定；B-折叠形成的多肽模型；依赖NAD的异柠檬酸脱氢酶底物结合位点的核磁共振研究；小三级结构的多肽模型；分子内二烯环锆化；分子内二烯环锆化；分子筛中气体吸附的Xe-129核磁共振光谱；以及取代的膦酸盐合成。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果在聚合物和催化等领域以及生物学中都是有用的。

This award from the Chemistry Research Instrumentation and Facilities program will help the Department of Chemistry at the University of Delaware acquire a 400 MHz spectrometer which will be used in the following research investigations: Structure Determination of Synthetic Peptide Analogs of G-Proteins; Peptide Model for B-sheet Formation; NMR Studies of Substrate Binding Sites of NAD-Dependent Isocitrate Dehydrogenase; Peptide Models of Small Tertiary Structures; Intramolecular Diene Cyclozirconation; Xe-129 NMR Spectroscopy of the Gas Sorbed in Zeolites; and Substituted Phosphonate Syntheses. Nuclear Magnetic Resonance (NMR) Spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in areas such as polymers and catalysis, and in biology.