Purchase of a 400 MHz NMR Spectrometer for Research and Teaching

购买 400 MHz NMR 波谱仪用于研究和教学

• 批准号: 0320649
• 负责人: Geoffrey Coates
• 金额: $ 36.25万
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0320649&HistoricalAwards=false
• 关键词: Purchase; 400; MHz; NMR; Spectrometer

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Cornell University will acquire a 400 MHz NMR Spectrometer. This equipment will enable researchers to carry out research on a) the structure and redox activity of nanostructured dendrimers; b) the quantitative analysis of isotopic isomers needed to test dynamical theories of intramolecular rearrangements; c) the development of catalysts for the controlled synthesis of polymers with novel structures; d) the solution phase structure-reactivity relations of widely used organolithium reagents; e) studies on how protein structure controls redox- and photochemistry in biological catalysis and signal transduction; and f) the synthesis of transition metal complexes with bulky ligands and the mechanisms of these complexes interacting with small molecules. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in polymer chemistry and biochemistry.

有了这项来自主要研究仪器（MRI）计划的奖项，康奈尔大学化学系将获得一台400 MHz NMR光谱仪。该设备将使研究人员能够开展以下方面的研究：a）纳米结构树枝状聚合物的结构和氧化还原活性; B）测试分子内重排动力学理论所需的同位素异构体的定量分析; c）控制合成具有新结构的聚合物的催化剂的开发; d）广泛使用的有机锂试剂的溶液相结构-反应性关系; e）研究蛋白质结构如何控制生物催化和信号传导中的氧化还原和光化学;以及f）具有大体积配体的过渡金属络合物的合成以及这些络合物与小分子相互作用的机制。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对聚合物化学和生物化学产生影响。