Acquisition of an Automated DNA Sequencer

获取自动 DNA 测序仪

基本信息

  • 批准号:
    9317625
  • 负责人:
  • 金额:
    $ 8.9万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    1994
  • 资助国家:
    美国
  • 起止时间:
    1994-01-01 至 1996-06-30
  • 项目状态:
    已结题

项目摘要

9317625 Hartl Five senior faculty at Harvard University are applying for an Applied Biosystems Model 373A-01 Automated DNA Sequencer with associated hardware and software. Harvard is in a unique position to lead a new synthesis of molecular biology and evolutionary biology because of its long tradition of excellence in both fields. Indeed, among the priorities for academic growth and development in the life sciences is the overlap between molecular biology and evolutionary biology. The Department of Organismic and evolutionary Biology (OEB) at Harvard is already expanding with new faculty representing this type of integration. Among the five OEB faculty participating, four (Hartl, Donoghue, Kellogg, and Pierce) are new to Harvard, and three (Hartl, Donoghue, and Pierce) are senior appointments. The need for automated DNA sequencing in the participating groups is immediate and acute. There is no automated DNA sequencer available for shard use. Among the applicants, no group alone is large enough or its needs extensive enough to justify purchase, maintenance, and exclusive use of an automated sequencer. However, in the aggregate, the groups can make use of an automated sequencer essentially to full capacity (estimated sequencing needs approximately 1 million bp per year). The automated DNA sequencer will be set up in the Hartl laboratory, which is centrally located among the participating users, and will be supervised by Dr. Elena Lozovskaya, a member of the Hartl group who has extensive practical experience in automated DNA sequencing. Most of the participating groups have already had relevant experience using automated DNA sequencers and their projects are funded and ready to be implement. Therefore, the automated DNA sequencer is a familiar piece of equipment that will be set up in a central location among the users, supervised by an experienced investigator, and used immediately to essentially full capacity. OEB will contribute to the purchase of the instrument and support of the major portion of the recurring service contract. at Harvard University are applying for an Applied Biosystems Model 373A-01 Automated DNA Seq ! F $ $ ( Times New Roman Symbol & Arial " h E E E + ! = abstract Deseree King, BIR Deseree King, BIR
哈佛大学的五名高级教师正在申请一台应用生物系统公司的373 A-01型自动DNA测序仪及其相关的硬件和软件。 哈佛在引领分子生物学和进化生物学的新综合方面处于独特的地位,因为它在这两个领域都有着悠久的卓越传统。 事实上,生命科学学术增长和发展的优先事项之一是分子生物学和进化生物学之间的重叠。 哈佛的器官和进化生物学系(OEB)已经在扩大,新的教师代表了这种类型的整合。 在参加OEB的五位教师中,有四位(哈特尔、多诺霍、凯洛格和皮尔斯)是哈佛的新人,三位(哈特尔、多诺霍和皮尔斯)是高级任命。 参与小组对自动DNA测序的需求是迫切和紧迫的。 没有自动DNA测序仪可用于碎片使用。 在申请人中,没有一个团体足够大,或者其需求足够广泛,以证明购买、维护和独家使用自动测序仪是合理的。 然而,总的来说,这些小组可以充分利用自动测序仪(估计测序每年需要约100万bp)。 自动DNA测序仪将安装在Hartl实验室,该实验室位于参与用户的中心,并将由Hartl小组成员Elena Lozovskaya博士监督,他在自动DNA测序方面拥有丰富的实践经验。 大多数参与小组已经拥有使用自动DNA测序仪的相关经验,其项目已获得资助并准备实施。 因此,自动DNA测序仪是一种熟悉的设备,将安装在用户之间的中央位置,由经验丰富的调查员监督,并立即使用到基本满负荷。OEB将为购买仪器和支持经常性服务合同的主要部分做出贡献。 在哈佛大学的应用生物系统模型373 A-01自动DNA测序申请 ! F $ $ ( Times New Roman 符号Arial& " H e e e + ! = 摘要 Deseree King,BIR Deseree King,BIR

项目成果

期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
专利数量(0)

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Daniel Hartl其他文献

A selectively driven molecular clock
一个选择性驱动的分子钟
  • DOI:
    10.1038/281230a0
  • 发表时间:
    1979-09-01
  • 期刊:
  • 影响因子:
    48.500
  • 作者:
    Daniel Hartl;Daniel Dykhuizen
  • 通讯作者:
    Daniel Dykhuizen

Daniel Hartl的其他文献

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{{ truncateString('Daniel Hartl', 18)}}的其他基金

DISSERTATION RESEARCH: The Genetic Architecture of a Chromosomal Inversion
论文研究:染色体倒位的遗传结构
  • 批准号:
    1311260
  • 财政年份:
    2013
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant
Molecular Evolvability In Theory And In A Bacterial Drug-Resistence Gene
理论和细菌耐药基因的分子进化
  • 批准号:
    0343598
  • 财政年份:
    2004
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant
DISSERTATION RESEARCH: Molecular Evolutionary Genetics of Mating Behavior in the Genus Drosophila
论文研究:果蝇属交配行为的分子进化遗传学
  • 批准号:
    0309054
  • 财政年份:
    2003
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant
U.S.-France Cooperative Research: Population Dynamics and Evolution of Drosophila Transposable Elements
美法合作研究:果蝇种群动态和转座元件的进化
  • 批准号:
    9216305
  • 财政年份:
    1993
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant
Genetic, Molecular, and Population Studies of Sd
Sd 的遗传、分子和群体研究
  • 批准号:
    7700886
  • 财政年份:
    1978
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant
Genetic and Population Studies of Segregation Distortion
分离扭曲的遗传和群体研究
  • 批准号:
    7419708
  • 财政年份:
    1974
  • 资助金额:
    $ 8.9万
  • 项目类别:
    Standard Grant

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