Molecular Genetics of Fission Yeast Course

9405372 Grodzicker这笔赠款支持冷泉港实验室课程，分子遗传学裂变酵母，将在1994年至1998年秋季举行。 该课程提供了一个简短的，两个星期，在经典和分子方法的密集培训，使用裂变酵母作为实验生物。 它的目的是准备学生直接进入研究，利用先进的和/或专门的技术和概念，分子遗传学，经典遗传学和生物化学，可以应用于许多研究，包括细胞周期调控和生长控制。 重点不仅放在技术上，而且放在解决实验问题的方法上。 该课程旨在指导学生在三个主要领域。 在第一个课程中，即裂变酵母的细胞生物学中，学生获得了使用荧光探针进行显微镜检查的专业知识。 此外，最先进的细胞周期分析技术，如流式细胞术和淘洗细胞同步。 生物化学实验也提出，使学生能够连接遗传和生物化学数据，并准备他们将这些方法与自己的工作。 该课程还提供了在酵母中可能进行的强大的经典遗传分析的科学专业知识。 学生学习识别突变基因、绘制基因图和四分体分析的方法。 最后，学生获得分子遗传学的专业知识。 学生接受在酵母研究中使用重组DNA技术的理论和实践培训。 教师是根据他们对该领域的贡献和知识来选择的。 教员们邀请讲师就当前的研究作最新的报告。 所有讲师都在各自的领域做出了重大贡献。 受训人员从研究生到高级调查员不等，由课程教员挑选。 %此补助金支持1994-1998年秋季在冷泉港实验室举办的裂变酵母分子遗传学年度两周课程。 由于课程时间短，无论是高年级还是低年级的学生都可以在一个远离其他时间和注意力要求的环境中参加并接受短期的密集培训。 该课程为科学家提供了一个不寻常的机会，让他们在另一个专业进行再培训，或将新领域的工作应用于自己的研究兴趣。 ***

9405372 Grodzicker This grant supports the Cold Spring Harbor Laboratory course, The Molecular Genetics Fission Yeast, to be held in the fall of 1994-1998. The course provides a short, two week, intensive training in classical and molecular approaches to the use of fission yeast as an experimental organism. It is designed to prepare the student to enter directly into research that makes use of advanced and/or specialized techniques and concepts in molecular genetics, classical genetics and biochemistry that can be applied to many studies, including cell cycle regulation and growth control. The emphasis is placed not only on techniques but on the approaches to experimental problems. The course is organized to instruct students in three major areas. In the first, which is the cell biology of fission yeast, students gain expertise in the use of fluorescent probes for microscopy. In addition, state of the art techniques for cell cycle analysis, such as flow cytometry and synchronization of cells by elutriation are presented. Biochemical experiments are also presented to enable students to connect genetic and biochemical data and prepare them to relate these approaches to their own work. The course also provides scientific expertise in the powerful classical genetic analyses possible in yeast. Students learn approaches to identifying mutant genes, mapping genes and to tetrad analysis. Finally, students gain expertise in molecular genetics. Students are trained in the theory and practice of the use of recombinant DNA technology in studies in yeast. The faculty are chosen on the basis of their contributions to and knowledge of field. The faculty invite lecturers who give up-to-the-minute reports on current research. The lecturers have all made significant contributions to their fields. The trainees range from graduate students to senior investigators, and are chosen by the course faculty. %%% This grant supports an annual two-week course in the molecular genetics of fission yeast at Cold Spring Harbor Laboratory in the fall of 1994-1998. Because of the short duration of the course, senior, as well as junior individuals can attend and receive a short, intense period of training in an environment remote from other demands on their time and attention. The course provides an unusual opportunity for scientists to retrain in another speciality or to apply the work of a new field to their own research interests. ***