Integration of FT-NMR Instrument in the Undergraduate Curriculum

[451761]埃利亚松获得一台傅里叶变换核磁共振光谱仪将大大改善化学课程。新仪器将使学生能够亲自记录自己的光谱，这在教学上优于单纯的书本教学，而且亲身体验一直是我们系的一个重要目标。本方案的目标是在二年级有机化学课程中尽早介绍基本的1H、13C、DEPT、1H- 1H COSY和1H-13C COSY技术。这将有助于重组第二和第三年的实验课程，以提供让所有学生参与研究导向经验的实验。实验室学生将被组织成研究小组。该小组将进行实验，讨论实验设计和程序，收集和审查数据，并在必要时得出结论并设计新的实验。不像其他项目，实验室课程是一个纯粹的研究项目，我们的计划是提供一个混合的标准和开放式实验。我们的目标是提供一个研究型的氛围，同时提供一个环境，让学生体验切实的成功，从而提供发现的兴奋，吸引学生进入我们的本科研究项目。有机、生物物理、生物化学和物理化学的实验课程将受到这一提议的严重影响。使用1H- 1H COSY作为教学工具，将有助于提高1H NMR基础理论教学的有效性。在有机定性分析和生物化学中，将展示一维和二维核磁共振技术解决结构问题的能力。在我们努力修订基础实验课程的同时，我们建议学生正式参与一个结构化的研究项目。项目团队将由两个或更多的教师组成，以开发跨学科项目，而不是由单个教师与单个学生合作。将特别努力招收生物/化学双专业的学生，他们往往不参与研究，以增加他们的参与。

9451761 Eliason The acquisition of an FT-NMR spectrometer will significantly improve the chemistry curriculum. The new instrument will give the students the hands-on ability to record their own spectra which is pedagogically superior to book instruction alone, and a hands-on experience has always been an important objective for our department. A goal of this proposal is to introduce basic 1H, 13C, DEPT, 1H- 1H COSY and 1H-13C COSY techniques early in the sophomore organic chemistry course. This will assist in restructuring the laboratory curriculum of the second and third years to provide experiments that engage all students in a research oriented experience. Laboratory students will be organized into research like teams. The team will be given an experiment, will discuss experimental design and procedures, will collect and review data, and will draw conclusions and design new experiments as necessary. Unlike other programs in which the laboratory curriculum is a pure research project, our plan is to provide a mixture of standard and open ended experiments. Our goal is to provide a research type atmosphere while at the same time providing an environment in which the student experiences tangible success thereby providing the excitement of discovery to attract students into our undergraduate research program. The laboratory curriculum of organic, biophysical, biochemistry and physical chemistry will be heavily impacted by this proposal. The effectiveness of teaching of the basic theory of 1H NMR will be aided with the use of 1H- 1H COSY as a teaching tool. The power of 1-D and 2-D NMR techniques to solve structural problems will be shown both in organic qualitative analysis and in biochemistry. Concurrent with our efforts to revise our basic laboratory curriculum we propose to formalize the involvement of students in a structured research program. Instead of a single faculty member working with a single student, project teams consisting of two or more faculty will be formed to develop cross discipline projects. A special effort to recruit dual biology/chemistry major students, who have tended not to be involved in research, will be made to increase their participation.