Sequential Integration of FT-NMR for Science Majors in the Chemistry Curriculum

该项目包括对我们目前的60兆赫连续波核磁共振波谱仪进行硬件/软件升级，使其能够作为多核FT仪器发挥作用。我们寻求让尽可能多的理科学生亲身接触到各种各样的现代化学仪器技术。相对较短的光谱获取时间，加上离线数据还原和分析，将使维滕贝格的所有理科专业学生都能获得使用这种现代光谱技术的经验。此外，在化学课程的广泛课程中，化学专业的学生将利用这种技术作为一种普遍存在的静态和动态分子结构的探测器。课程早期部分的顺序性质允许以分层的方式向学生介绍FT-核磁共振实验的各个方面，其中每个主题都建立在先前的知识和技能的基础上。实验将包括在普通化学中使用FT-核磁共振作为磁性和电负性的间接探针，在有机化学中通过1H和13C核磁共振谱进行结构分析，在分析化学中进行定量分析，在物理化学中进行动力学分析和松弛时间研究，在生物化学中使用1H和31P谱进行结构研究，在无机化学中使用1H、13C、31P和11B谱进行静态和动态分析。

This project involves the acquisition of a hardware/software upgrade to our current 60 Mhz continuous wave NMR spectrometer that will allow it to function as a multinuclear, FT instrument. We seek to have the largest number of science students possible get hands-on exposure to a wide variety of modern instrumental techniques in chemistry. The relatively short spectrum acquisition time, coupled with off-line data reduction and analysis, will allow all science majors at Wittenberg to get experience using this modern spectroscopic technique. Further, in a wide range of courses in the Chemistry curriculum, chemistry majors will utilize this technique as a ubiquitous probe of static and dynamic molecular structure. The sequential nature of the early part of the curriculum allows the students to be introduced to various aspects of the FT-NMR experiment in a layered fashion, where each topic builds upon prior knowledge and skills. Experiments will include the use of FT-NMR as an indirect probe of magnetism and electronegativity in general chemistry, structure analysis by 1H and 13C NMR spectra in organic chemistry, quantitative analysis in analytical chemistry, kinetics analysis and relaxation time studies in physical chemistry, structure in biochemistry using 1H and 31p spectra, and static and dynamic analysis in inorganic chemistry using 1H, 13C, 31p, and 11B spectra.