Integration of FT-NMR Spectroscopy Throughout the Chemistry Curriculum

将 FT-NMR 波谱学融入整个化学课程

• 批准号: 9952794
• 负责人: Daryl Cox
• 金额: $ 4.04万
• 依托单位: Southern Nazarene University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-02-15 至 2003-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9952794&HistoricalAwards=false
• 关键词: Integration; FT; NMR; Spectroscopy; Throughout

Chemistry (12) Fourier transform applications to NMR have revolutionized chemical inquiry. FT-NMR spectroscopy plays an essential role in the undergraduate chemistry curriculum. In this project, an older continuous-wave NMR which has been converted to a modern multinuclear Anasazi EFT-60 FT- NMR plays a key role in achieving the goal of obtaining the sophistication and speed of FT-NMR. Such upgrades have proven to be a low-maintenance and cost-effective alternative to expensive high-field NMR spectrometers for small undergraduate schools. The long-term goal is the integration FT-NMR spectroscopy throughout the curriculum to produce graduates educated in the technical and scientific aspects of modern FT-NMR spectroscopy. Beginning with the freshman courses (General Chemistry, General Chemistry for Allied Health Professions, and Chemistry , Environment and Health) students are introduced to FT-NMR spectroscopy both theoretically and experientially through a series of experiments designed to require "hands-on" involvement. As students progress through the chemistry curriculum (Organic, Instrumental Analysis, Biochemistry, Advanced Inorganic and Physical Chemistry) they perform experiments that develop technical competency in preparing samples and running routine 1H and 13C NMR spectra. By graduation, the chemistry major experiences 2D- and heteronuclear techniques by means of thorough, well-planned experiments that demonstrate the breadth and applications of modern FT-NMR spectroscopy. These experiments are introduced in a measured incremental fashion and are adapted from recent literature (primarily the J. Chemical Education). The non-science major is introduced to FT-NMR spectroscopy so they can respect and appreciate the necessity of sophisticated instrumentation in modern chemistry. Continuous assessments using both external (Advisory Board) and internal evaluations provide feedback and guidance on the success of the project as a significant curricular enhancement.

化学（12）傅立叶变换在核磁共振中的应用彻底改变了化学研究。 FT-NMR光谱学在本科化学课程中起着至关重要的作用。 在这个项目中，一个旧的连续波NMR已被转换为一个现代的多核Anasazi EFT-60 FT-NMR在实现目标的复杂性和速度的FT-NMR起着关键作用。 这种升级已被证明是一个低维护和成本效益的替代昂贵的高场核磁共振光谱仪的小型本科学校。长期目标是在整个课程中整合FT-NMR光谱，以培养在现代FT-NMR光谱的技术和科学方面接受教育的毕业生。从新生课程（普通化学，普通化学联合健康诊断，化学，环境和健康）开始，学生通过一系列旨在要求“动手”参与的实验，从理论和经验上介绍FT-NMR光谱。随着学生学习化学课程（有机、仪器分析、生物化学、高级无机和物理化学），他们会进行实验，培养制备样品和运行常规1H和13 C NMR光谱的技术能力。通过毕业，化学专业通过全面，精心策划的实验来体验2D和异构技术，这些实验展示了现代FT-NMR光谱的广度和应用。 这些实验是在一个测量增量的方式介绍，并改编自最近的文献（主要是J.化学教育）。 非科学专业的学生被引入FT-NMR光谱学，这样他们就可以尊重和欣赏现代化学中复杂仪器的必要性。 利用外部（咨询委员会）和内部评估进行的持续评估为项目的成功提供了反馈和指导，这是一项重大的课程改进。