Adherent Zirconi Surface on Cobalt Chromium Alloy Prostheses

钴铬合金假体上的粘附氧化锆表面

• 批准号: 9460066
• 负责人: Stephen Bunker
• 金额: $ 6.48万
• 依托单位: Implant Sciences Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-01-01 至 1995-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9460066&HistoricalAwards=false
• 关键词: Adherent; Zirconi; Surface; Cobalt; Chromium

Zirconia has been found to produce one of the lowest rates of polyethylene wear debris when used with ultrahigh molecular weight polyethylene for the articulating surface of a prosthesis. A zirconia coating can combine these useful surface properties with the well known bulk properties of common medical alloys. Due to the lack of chemical cohesion of zirconia with the elements of cobalt chromium alloy, even deposition techniques which blend the interface between coating and substrate (functionally gradient interface) are not producing sufficient adhesion. Implant Sciences Corporation proposes to demonstrate that a combination of a chemical bonding layer with fully blended interfaces is a solution to the adhesion problem when the layers are formed using energetic metal ions of the appropriate species. The proposed coating process is omni-directional, has a very high rate of throughput, and is proven for large batch commercial production. Orthopedic manufacturers are greatly interested in extending the working lifetimes of their total joint replacement components. The proposed coating method combines the wear rates of ceramic surfaces with the established manufacturing capability of traditional alloy prostheses. The combination results in maximum gain in performance for minimum cost impact. Several hundred thousand total joint replacement operations are performed each year.

当与超高分子量聚乙烯一起用于假体的关节表面时，氧化锆已被发现产生聚乙烯磨损碎片的最低率之一。氧化锆涂层可以将这些有用的表面特性与常见医用合金众所周知的体积特性结合起来。由于氧化锆与钴铬合金元素缺乏化学黏结力，即使是混合涂层与基体之间的界面（功能梯度界面）的沉积技术也不能产生足够的附着力。植入科学公司提议证明，当使用适当种类的高能金属离子形成层时，具有完全混合界面的化学键合层的组合是解决粘附问题的一种方法。所提出的涂层工艺是全方位的，具有非常高的吞吐率，并证明了大规模的商业生产。骨科制造商对延长其全关节置换部件的工作寿命非常感兴趣。所提出的涂层方法将陶瓷表面的磨损率与传统合金假体的制造能力相结合。这一组合以最小的成本影响获得了最大的性能增益。每年进行数十万例全关节置换手术。