Adherent Zirconi Surface on Cobalt Chromium Alloy Prostheses

已发现，当与超高相对分子质量聚乙烯一起用于假体的关节表面时，氧化锆会产生最低的聚乙烯磨损碎屑。氧化锆涂层可以将这些有用的表面特性与常见医用合金众所周知的块状特性结合在一起。由于氧化锆与钴铬合金元素之间缺乏化学结合力，即使是将涂层和基材之间的界面(功能梯度界面)混合在一起的沉积技术也不能产生足够的附着力。植入物科学公司建议证明，当使用适当物种的高能金属离子形成层时，将化学粘合层与完全混合的界面相结合是解决粘合问题的一种解决方案。所提出的涂布工艺是全方位的，具有很高的生产能力，并被证明是大批量的商业生产。整形外科制造商对延长其全部关节置换部件的工作寿命非常感兴趣。建议的涂层方法结合了陶瓷表面的磨损率和传统合金假体的既定制造能力。这一组合可最大限度地提高性能，从而将成本影响降至最低。每年总共进行数十万次关节置换手术。

Zirconia has been found to produce one of the lowest rates of polyethylene wear debris when used with ultrahigh molecular weight polyethylene for the articulating surface of a prosthesis. A zirconia coating can combine these useful surface properties with the well known bulk properties of common medical alloys. Due to the lack of chemical cohesion of zirconia with the elements of cobalt chromium alloy, even deposition techniques which blend the interface between coating and substrate (functionally gradient interface) are not producing sufficient adhesion. Implant Sciences Corporation proposes to demonstrate that a combination of a chemical bonding layer with fully blended interfaces is a solution to the adhesion problem when the layers are formed using energetic metal ions of the appropriate species. The proposed coating process is omni-directional, has a very high rate of throughput, and is proven for large batch commercial production. Orthopedic manufacturers are greatly interested in extending the working lifetimes of their total joint replacement components. The proposed coating method combines the wear rates of ceramic surfaces with the established manufacturing capability of traditional alloy prostheses. The combination results in maximum gain in performance for minimum cost impact. Several hundred thousand total joint replacement operations are performed each year.