Integration of Fourier Transform Nuclear Magnetic Resonance into the Undergraduate Chemistry Curriculum

本计画是将核磁共振的理论与实务整合到大学化学课程中。 有机化学实验室的初步实验侧重于H1，C13和NOE（核奥弗豪泽效应）光谱的解释，以及如何使用从化学位移，分裂模式，耦合常数和积分比获得的信息来阐明结构。 在随后的课程和实验室中，FT-NMR实验和仪器操作变量的性质正在研究，涉及反应动力学，顺磁性化合物的磁矩，分子内重排，2-D方法和其他应用的问题正在研究中。 在FT-NMR光谱仪的操作缺乏经验的本科生的教学正在增加的录像带，描述周围的磁铁，样品制备，仪器设置与逐步的计算机命令的各种实验，数据采集和处理，并介绍了光谱的安全。 此外，该部门正在进行一项推广计划，邀请附近学院的学生到我们的校园参加NMR研讨会和夏季研究机会。

This project is integrating nuclear magnetic resonance (NMR) theory and practice into the undergraduate chemistry curriculum. Initial experiments in organic chemistry laboratories focus on the interpretation of H1, C13, and NOE (Nuclear Overhauser Effect) spectra and how to elucidate structure using information obtained from chemical shifts, splitting patterns, coupling constants, and integration ratios. In subsequent coursework and laboratories, the nature of the FT-NMR experiment and instrument operating variables is being examined and problems involving reaction kinetics, magnetic moments of paramagnetic compounds, intramolecular rearrangements, 2-D methods, and other applications are being studied. Instruction of inexperienced undergraduates in the operation of the FT-NMR spectrometer is being augmented by video tapes that describe safety around magnets, sample preparation, instrument setup with step-by-step computer commands for the various experiments, data acquisition and processing, and the presentation of the spectra. The department additionally is conducting an outreach program whereby students at nearby colleges are invited to our campus for NMR workshops and summer research opportunities.