Integration of Fourier Transform-Nuclear Magnetic Resonance Spectroscopy and Gas Chromatography/Mass Spectrometry into the Undergraduate Curriculum

化学（12）本项目致力于通过实施解决问题，基于项目的有机化学实验室计划来振兴和改造化学课程。该计划为学生提供丰富的“动手”经验，特别是那些使用傅里叶变换核磁共振（FT-NMR）光谱仪和气相色谱-质谱仪（GC-MS）。学生积极学习有机化学的概念，使用FT-NMR和GC-MS来解决从出版的，成功的实验室实验，主要是从化学教育杂志改编的问题。 计划了几个学生项目，让学生参与NMR和GC-MS的获取和解释，例如通过极化转移（DEPT）13 C NMR光谱的质子解耦和无失真增强对烷烃的结构进行解析，以及通过GC-MS识别葡萄酒的芳香成分。这些仪器正被纳入其他实验室课程，如高级有机化学，其中学生表征有机锡化合物，以通过NMR探索杂原子自旋耦合和通过GCMS探索同位素分布模式，以及分析化学，学生分析银杏提取物的复杂混合物。学生的预期成果包括FT-NMR和GC-MS操作中的市场技能的发展，光谱数据解释能力的提高，对化学在社会中的效用的认识的提高，以及对化学的热情的提高。FT-NMR和GC-MS纳入化学课程也鼓励教师通过培训发展，以设计新的学生实验，并与本科生进行研究。学生熟练操作NMR和GC-MS计算机工作站也有助于将技术融入教育。

Chemistry (12) This project works to revitalize and transform the chemistry curriculum through the implementation of a problem-solving, project-based laboratory program for Organic Chemistry. This program provides students with enriching "hands on" experiences, especially those using a Fourier Transform Nuclear Magnetic Resonance (FT-NMR) spectrometer and a Gas Chromatograph-Mass Spectrometer (GC-MS). Students actively learn the concepts of organic chemistry using FT-NMR and GC-MS to solve problems adapted from published, successful laboratory experiments, largely from the Journal of Chemical Education. Several student projects are planned that engage students in the acquisition and interpretation of NMR and GC-MS, such as the structural elucidation of alkanes by proton-decoupled and distortionless enhancement by polarization transfer (DEPT) 13C NMR spectroscopy and the identification of the fragrant components of wine by GC-MS. In addition to Organic Chemistry, these instruments are being incorporated into other laboratory courses such as Advanced Organic Chemistry, wherein students characterize an organotin compound to explore heteronuclear spin coupling by NMR and isotope distribution patterns by GCMS, and Analytical Chemistry, wherein students analyze complex mixtures from Ginko extracts. Expected outcomes for students include the development of marketable skills in the operation of FT-NMR and GC-MS, improved ability in the interpretation of spectral data, increased awareness of the utility of chemistry in society, and heightened enthusiasm for chemistry. Incorporation of FT-NMR and GC-MS into the chemistry curriculum also encourages faculty development via training in order to design new student experiments and to conduct research with undergraduates. Proficient operation of the NMR and GC-MS computer workstations by students also serves to integrate technology into education.