Prototyping Biomolecular Computations
Prototyping Biomolecular Computations
批准号:
9725021
负责人:
John Reif
金额:
$264.79万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-09-01 至 2002-04-30
中文摘要
生物分子计算(BMC)是一个具有巨大潜力的领域,因为在分子尺度上可以获得大量的并行性。 然而,现实的评估还必须考虑到,这一领域的研究由于不成熟而具有相当大的风险。 这是一个多组的努力,包括美国境内的几个小组在BMC工作。 这个项目的目标是组织这些团体的能量,以便利用集体的成就,可能超过个人的努力。该项目将强调支持BMC的基础设施的协作开发,以进一步开发和测试其基本能力。 这些小组将调查BMC的关键方面。 这些将包括:BMC的演示。 关键的子项目是:文字设计;用于存储和检索逻辑和数字信息的寄存器设计;诸如逻辑和算术运算之类的基本运算的执行,以及这些运算的顺序链接;数据的输入和结果的读出以及与硅基计算机的接口;以及提高错误恢复能力的方法。新3D结构的纳米构建。BMC的应用 这将包括:生物学应用探索与演示NP难搜索问题模拟问题求解软件工具。 用于仿真、设计和相关的数学模型。
英文摘要
Biomolecular Computation (BMC) is an area of great potential due to the massive parallelism available at the molecular scale. However, a realistic assessment must also take into account that research in this area possesses considerable risk, due to its lack of maturity. This is a multi-group effort encompassing several groups within the United States working on BMC. The goal of this project is to organize the energies of these groups so as to harness a collective accomplishments that may exceed the individual efforts. This project will emphasize collaborative development of the infrastructure in support of BMC, to further develop and test its basic capabilities. The groups will investigate key aspects of BMC. These will include: Demonstrations of BMC. The key subtakes are: word design; register design for storage and retrieval of logical and numeric information; execution of basic operations such as logical and arithmetric operations, and the sequential chaining of these operations; input of data and readout of results and interfacing with silicon-based computers; and methods to improve error resiliency. Nano-construction of New 3D Structures. Applications of BMC. This will include: biological applications exploration and demonstrations of intractable NP search problems solution of analog problems Software Tools. For simulation, design and associated mathematical models.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
SHF: Small: High-speed DNA polymerase CRNs for signal amplification, oscillation, consensus, and linear control
-
批准号:2113941
-
项目类别:Standard Grant
-
资助金额:$50.0万
-
财政年份:2021
-
负责人:John Reif
-
依托单位:
NSF Student Travel Grant for Sixteenth Conference on the Foundations of Nanoscience (FNANO 2019)
-
批准号:1851695
-
项目类别:Standard Grant
-
资助金额:$1.2万
-
财政年份:2019
-
负责人:John Reif
-
依托单位:
SHF: Small: Distributed DNA Computations Operating on a Collection of Cell Membranes
-
批准号:1909848
-
项目类别:Standard Grant
-
资助金额:$30.0万
-
财政年份:2019
-
负责人:John Reif
-
依托单位:
SHF: Small: Hot DNA Computation: Speeding up DNA-based Computation, CRNs, and Robotics using Strand-Displacing Polymerase
-
批准号:1813805
-
项目类别:Standard Grant
-
资助金额:$22.5万
-
财政年份:2018
-
负责人:John Reif
-
依托单位:
Support of 15th Annual Conference on the Foundations of Nanoscience (FNANO 2018)
-
批准号:1748415
-
项目类别:Standard Grant
-
资助金额:$1.2万
-
财政年份:2018
-
负责人:John Reif
-
依托单位:
Support of 14th Annual Conference on the Foundations of Nanoscience (FNANO 2017)
-
批准号:1709472
-
项目类别:Standard Grant
-
资助金额:$1.2万
-
财政年份:2017
-
负责人:John Reif
-
依托单位:
SHF: Small: DNA Circuits for Analog Computations
-
批准号:1617791
-
项目类别:Standard Grant
-
资助金额:$30.8万
-
财政年份:2016
-
负责人:John Reif
-
依托单位:
SHF: Small: Localized DNA Hybridization Computation
-
批准号:1320360
-
项目类别:Standard Grant
-
资助金额:$40.0万
-
财政年份:2013
-
负责人:John Reif
-
依托单位:
SHF: Small: Error Correction for Biomolecular Computations
-
批准号:1217457
-
项目类别:Standard Grant
-
资助金额:$45.0万
-
财政年份:2012
-
负责人:John Reif
-
依托单位:
EAGER: Exploratory Software Development & Experiments of Dynamic DNA Nanosystems
-
批准号:1141847
-
项目类别:Standard Grant
-
资助金额:$20.0万
-
财政年份:2011
-
负责人:John Reif
-
依托单位:
EMT/NANO: Autonomous Programmable DNA Devices Using DNAzymes
-
批准号:0829797
-
项目类别:Standard Grant
-
资助金额:$20.0万
-
财政年份:2008
-
负责人:John Reif
-
依托单位:
EMT/NANO: Polymerase-Based Self-Activating and Reactivating DNA Systems
-
批准号:0829798
-
项目类别:Continuing Grant
-
资助金额:$50.0万
-
财政年份:2008
-
负责人:John Reif
-
依托单位:
NANO: EMT: A DNA-Based Autonomous Programmable Molecular Transport Network
-
批准号:0523555
-
项目类别:Continuing Grant
-
资助金额:$40.0万
-
财政年份:2005
-
负责人:John Reif
-
依托单位:
WORKSHOP: NSF Workshop on Emerging Opportunities of Nanoscience to Energy Conversion and Storage
-
批准号:0551965
-
项目类别:Standard Grant
-
资助金额:$0.0万
-
财政年份:2005
-
负责人:John Reif
-
依托单位:
EMT: NSF Workshop on Programmed Self-Assembly
-
批准号:0523558
-
项目类别:Standard Grant
-
资助金额:$3.0万
-
财政年份:2005
-
负责人:John Reif
-
依托单位:
Nano: Error-Resilient DNA Tiling Assemblies
-
批准号:0432038
-
项目类别:Continuing Grant
-
资助金额:$29.4万
-
财政年份:2004
-
负责人:John Reif
-
依托单位:
SGER: Micro and Nano-Robotics Motion Control and Self Assembly Algorithms
-
批准号:0094604
-
项目类别:Standard Grant
-
资助金额:$8.08万
-
财政年份:2000
-
负责人:John Reif
-
依托单位:
ITR: Self-Assembly of DNA Nano-Scale Structures for Computation
-
批准号:0086015
-
项目类别:Continuing Grant
-
资助金额:$202.0万
-
财政年份:2000
-
负责人:John Reif
-
依托单位:
SGER: Design of a Biomolecular Distributed Operating Systems
-
批准号:9810000
-
项目类别:Standard Grant
-
资助金额:$5.0万
-
财政年份:1998
-
负责人:John Reif
-
依托单位:
Robust, Adaptive and Dynamic Robotic Motion Planning
-
批准号:9619647
-
项目类别:Continuing Grant
-
资助金额:$29.0万
-
财政年份:1997
-
负责人:John Reif
-
依托单位:
海外基金