Colaborative Research: Accessing Brain Collection Informationand Images Via Internet, CD-Rom and Centralized Location

合作研究：通过互联网、CD-ROM 和集中位置访问大脑采集信息和图像

• 批准号: 9814911
• 负责人: John Johnson
• 金额: $ 22.57万
• 依托单位: Michigan State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2003-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9814911&HistoricalAwards=false
• 关键词: Colaborative; Research; Accessing; Brain; Collection

To understand brain function, we need to understand brain structure. The evolution of mammals has led to many differences in brain anatomy, but we know very little how those differences correlate to the wide diversity of animal behavior. This collaborative project is to consolidate and make more accessible for research and education two major collections that form a unique, extensive, remarkably preserved assembly of comparative mammalian brain specimens. Together they contain more than 275 sectioned and stained brains, including over a half million microscope slides, representing over 150 species, from 50 Families in 17 different Orders of Mammalia. Many specimens are irreplaceable, from rare or endangered species, and so can provide critically unique data for questions about biodiversity. The collections are being brought to a national museum facility in Washington DC to join complementary extensive human brain collections, and so establish a single site for storage, curation, and research on comparative mammalian brain neuroanatomy. An electronic/website also is being developed, including several selected images, which researchers could access worldwide for data, or use to evaluate whether to make a research visit to the site itself to examine the original material. The impact of this project is high. First, it safely preserves for future research an irreplaceable resource that also represents a scientific investment of more than 50 years of exacting work by dozens of people. Second, it promotes multidisciplinary research on comparative neuroscience, behavior, and systematics to understand the diversity in the most complex organ known, adding computational expertise for technological development of digital imaging and multidimensional databases. Third, it provides a working base as well as a model for sharing complex morphological data with other collections, such as those on non-mammalian vertebrate brains. Fourth, the project will have educati onal as well as research impact by providing easy website access to information about the vertebrate brain in the context of biodiversity.

要了解大脑的功能，我们需要了解大脑的结构。 哺乳动物的进化导致了大脑解剖学上的许多差异，但我们对这些差异与动物行为的广泛多样性之间的关系知之甚少。 这个合作项目是为了巩固和使研究和教育更容易获得两个主要的集合，形成一个独特的，广泛的，保存完好的比较哺乳动物大脑标本的组装。 它们总共包含超过275个切片和染色的大脑，包括超过50万个显微镜载玻片，代表150多个物种，来自17个不同的哺乳动物目的50个科。 许多标本是不可替代的，来自稀有或濒危物种，因此可以为生物多样性问题提供关键的独特数据。 这些收藏品将被带到华盛顿特区的一个国家博物馆设施，加入互补的广泛的人类大脑收藏，从而建立一个单一的存储，策展和比较哺乳动物大脑神经解剖学研究的网站。 还正在开发一个电子/网站，其中包括若干选定的图像，研究人员可以在世界各地查阅这些图像以获取数据，或用于评估是否对网站本身进行研究访问以检查原始材料。 这个项目的影响很大。 首先，它为未来的研究安全地保存了一种不可替代的资源，这也是数十人50多年来严格工作的科学投资。 其次，它促进了比较神经科学，行为学和系统学的多学科研究，以了解已知最复杂器官的多样性，为数字成像和多维数据库的技术发展增加了计算专业知识。 第三，它提供了一个工作基础，以及与其他集合，如非哺乳动物的脊椎动物的大脑共享复杂的形态学数据的模型。 第四，该项目将通过在生物多样性的背景下提供有关脊椎动物大脑信息的简单网站访问，产生教育和研究影响。