Integration of a GC-Ion Trap Mass Spectrometer into the Undergraduate Chemistry Curriculum

将 GC-离子阱质谱仪纳入本科化学课程

• 批准号: 9851180
• 负责人: Timothy Sherwood
• 金额: $ 4.08万
• 依托单位: Arkansas Tech University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-15 至 2000-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9851180&HistoricalAwards=false
• 关键词: Integration; GC; Ion; Trap; Mass

This project focuses on improvements in upper division chemistry laboratories that would be fostered by the acquisition of a GC-ion trap mass spectrometer. In the upper division laboratories, the students perform comprehensive investigations beyond what is normally fond in many 'cookbook" type laboratory experiments. Each project lasts for two to four weeks, and includes some library research, sample preparation, and method development. The GC-MS is an integral part in several of these laboratory projects. The mass spectrometry of large biomolecules has become an increasingly powerful bioanalytical technique. Due to the size and cost of the necessary instrumentation, biological mass spectrometry is absent from most undergraduate curricula. In this project an experiment is being developed using the GC-ion trap that integrates the methodology of bioanalytical mass spectrometry into the course curriculum. Undergraduate research projects focusing on GC-MS method development and gas-phase thermochemistry are also underway. Arkansas's abundant natural resources foster many opportunities for environmentally related research projects. One example focuses on relating the aromatics emanating from various bird nests to the senses of predators. We also are utilizing the GC-ion trap mass spectrometer in the organic laboratory to aid in the identification products from organic syntheses.

这个项目的重点是改进高级化学实验室，这将通过获得gc -离子阱质谱仪来促进。在高级实验室，学生们进行全面的调查，而不是在许多“食谱”式的实验室实验中通常喜欢的。每个项目持续两到四周，包括一些图书馆研究、样品准备和方法开发。气相色谱-质谱是这些实验室项目中不可或缺的一部分。大型生物分子的质谱分析已成为一种日益强大的生物分析技术。由于必要仪器的尺寸和成本，生物质谱法在大多数本科课程中是缺席的。在这个项目中，正在开发一个使用gc离子阱的实验，该实验将生物分析质谱的方法整合到课程课程中。以气相色谱-质谱法开发和气相热化学为重点的本科生研究项目也在进行中。阿肯色州丰富的自然资源为环境相关的研究项目提供了许多机会。一个例子集中在将各种鸟巢发出的芳香与捕食者的感觉联系起来。我们还在有机实验室使用gc -离子阱质谱仪来帮助鉴定有机合成产物。