Integration of a GC-Ion Trap Mass Spectrometer into the Undergraduate Chemistry Curriculum

这个项目的重点是通过购买一台GC离子陷阱质谱仪来促进高级化学实验室的改进。在高级实验室中，学生们进行的全面调查超出了许多食谱类实验室实验通常所喜欢的范围。每个项目持续两到四周，包括一些图书馆研究、样品准备和方法开发。GC-MS是其中几个实验室项目中不可或缺的一部分。生物大分子的质谱学已经成为一种日益强大的生物分析技术。由于所需仪器的大小和成本，生物质谱学在大多数本科课程中都缺席。在这个项目中，正在使用GC离子捕捉器开发一个实验，它将生物分析质谱学的方法学整合到课程课程中。本科生的研究项目也在进行中，重点是GC-MS方法的开发和气相热化学。阿肯色州丰富的自然资源为与环境相关的研究项目提供了许多机会。其中一个例子着重于将各种鸟巢发出的芳香与捕食者的感觉联系起来。我们还利用有机实验室中的GC-离子陷阱质谱仪来帮助鉴定有机合成的产品。

This project focuses on improvements in upper division chemistry laboratories that would be fostered by the acquisition of a GC-ion trap mass spectrometer. In the upper division laboratories, the students perform comprehensive investigations beyond what is normally fond in many 'cookbook" type laboratory experiments. Each project lasts for two to four weeks, and includes some library research, sample preparation, and method development. The GC-MS is an integral part in several of these laboratory projects. The mass spectrometry of large biomolecules has become an increasingly powerful bioanalytical technique. Due to the size and cost of the necessary instrumentation, biological mass spectrometry is absent from most undergraduate curricula. In this project an experiment is being developed using the GC-ion trap that integrates the methodology of bioanalytical mass spectrometry into the course curriculum. Undergraduate research projects focusing on GC-MS method development and gas-phase thermochemistry are also underway. Arkansas's abundant natural resources foster many opportunities for environmentally related research projects. One example focuses on relating the aromatics emanating from various bird nests to the senses of predators. We also are utilizing the GC-ion trap mass spectrometer in the organic laboratory to aid in the identification products from organic syntheses.