XYZ on a Chip: Biomolecular Motor/Nanotube Integration for Actuator Nanotechnology

XYZ 芯片：用于执行器纳米技术的生物分子电机/纳米管集成

• 批准号: 0088509
• 负责人: Richard Superfine
• 金额: $ 110万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0088509&HistoricalAwards=false
• 关键词: XYZ; Chip; Biomolecular; Motor; Nanotube

0088509SuperfineThe goal of this research is to study the control over molecular motors with an engineering applications perspective, exploring ways in which these machines can be used in designed systems, e. g., the synthesis and delivery of pharmacological agents. The specific goals of this research are to: (1) demonstrate the control of the patterning of motor raceways as functioning tracks for the motion of motor proteins, (2) study the two main classes of proteins actin/myosin and microtubule/kinesin to understand their relative merits towards nanotechnology applications, (3) study the application of single motors and collections of motor proteins, (4) study the coupling of nanotubes to electrical circuitry through electro/dielectrokinesis at the nonometer scale, and (5) understand a processing methodology for incorporating nanometer scale ebeam lithography, nanotube placement/growth, patterned chemical functionalization and motor binding and motility.This award is co-funded by the Division of Engineering Education and Centers, the Division of Chemical and Transport Systems, and the Division of Bioengineering and Environmental Systems.

0088509 Superfine本研究的目标是从工程应用的角度研究对分子马达的控制，探索这些机器可用于设计系统的方法，例如。例如，在一个实施例中，药理学药剂的合成和输送。 这项研究的具体目标是：（1）证明对作为马达蛋白运动的功能轨道的马达滚道的图案化的控制，（2）研究两种主要类别的蛋白肌动蛋白/肌球蛋白和微管/驱动蛋白，以了解它们对纳米技术应用的相对优点，（3）研究单个马达和马达蛋白集合的应用，（4）通过纳米尺度的电/介电致动研究纳米管与电路的耦合，以及（5）理解结合纳米尺度电子束光刻、纳米管放置/生长、图案化化学功能化以及马达结合和运动的处理方法。该奖项由工程教育和中心部共同资助，化学和运输系统司以及生物工程和环境系统司。