CAREER: Cyclophane Carbenes: Nucleophilicity and Catalytic Applications

职业：环芳卡宾：亲核性和催化应用

• 批准号: 0092434
• 负责人: Steven Diver
• 金额: $ 51万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0092434&HistoricalAwards=false
• 关键词: CAREER; Cyclophane; Carbenes; Nucleophilicity; Catalytic

The nucleophility of imidazole and benzimidazole carbenes will be explored. Novel achiral and chiral [2.2] imidazolophanes will be synthesized and their nucleophilic reactivity investigated. The educational component of the plan will introduce a form of collaborative learning into an honors organic chemistry lab course. Students will be divided into small groups and visit several stations (self-contained experiments) during their lab periods. Outreach to elementary schools in terms of demonstrations and hands-on activities is also part of the educational plan.With this CAREER award, the Organic Synthesis Program is supporting the research and educational activities of Professor Steven T. Diver of the Department of Chemistry at the State University of New York, Buffalo. The fundamental chemistry of a class of compounds known as imidazole carbenes will be studied. Encapsulation of these carbenes into a rigid framework which may confer unusual properties onto these molecules will also be accomplished. The educational portion of the plan will continue the PI's visits to elementary schools to give demonstrations and allow the implementation of the PI's cooperative learning modules into an honors organic chemistry lab course.

咪唑和苯并咪唑卡宾的亲核性将被探讨。 本文将合成新型的非手性和手性[2.2]咪唑啉并研究其亲核反应性。 该计划的教育部分将引入一种合作学习的形式到荣誉有机化学实验室课程。 学生将被分成小组，并在实验期间参观几个站（独立实验）。 此外，在教学计划中，还将以示范和实践活动的形式深入到小学。有了这个CAREER奖，有机合成计划将支持Steven T.布法罗纽约州立大学化学系的潜水员。 将研究一类称为咪唑卡宾的化合物的基础化学。 也将完成将这些卡宾封装到刚性框架中，这可能赋予这些分子不寻常的性质。 该计划的教育部分将继续PI访问小学进行演示，并允许PI的合作学习模块实施到荣誉有机化学实验室课程中。