MRI: Acquisition of a Nuclear Magnetic Resonance System

MRI：核磁共振系统的采集

• 批准号: 0116145
• 负责人: Alex Roche
• 金额: $ 19.87万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116145&HistoricalAwards=false
• 关键词: MRI; Acquisition; Nuclear; Magnetic; Resonance

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Rutgers University in Camden will acquire a300 MHz nuclear magnetic resonance (NMR) Spectrometer with multinuclear capabilities and a variable temperature control module. This equipment will enable researchers to carry out studies on a) synthesis of fluorinated organic compounds; b) characterization of various monomers and their corresponding precursors; and c) the catalytic mechanisms of lipoamide dehydrogenase by probing native and mutated enzymes with and without substrate. The investigators will also integrate the NMR spectrometer into several undergraduate and graduate level courses. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including materials chemistry and biochemistry.

在主要研究仪器(MRI)计划的这一奖励下，卡姆登的罗格斯大学化学系将获得一台具有多核能力的300 MHz核磁共振(核磁共振)光谱仪和一个可变温度控制模块。该设备将使研究人员能够开展以下方面的研究：a)含氟有机化合物的合成；b)各种单体及其相应前体的表征；以及c)通过探测有底物和无底物的天然和突变酶来研究硫酰胺脱氢酶的催化机理。研究人员还将把核磁共振光谱仪整合到几门本科和研究生课程中。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对包括材料化学和生物化学在内的许多领域产生影响。