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MRI: Acquisition of a Nuclear Magnetic Resonance (NMR) Spectrometer for Research and Training at Central Michigan University

MRI：购买核磁共振 (NMR) 波谱仪用于中密歇根大学的研究和培训

基本信息

批准号：
2117338
负责人：
Benjamin Swarts
金额：
$ 34.44万
依托单位：
Central Michigan University
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=2117338&HistoricalAwards=false
关键词：
MRI Acquisition Nuclear Magnetic Resonance

项目摘要

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Central Michigan University is acquiring a 500 MHz nuclear magnetic resonance (NMR) spectrometer equipped with an automatic sample loader and a temperature control system to support research of Dr. Benjamin Swarts and colleagues Anja Mueller, Janice Tomasik, Choon Y Lee and Wenjun Du. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as permitting study of chemically and biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as collaborators from regional community colleges.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially impacts studies of carbohydrate/lipid synthesis, creating chemical tools to study bacteria and generating polysaccharide-based renewable materials. The instrumentation is also used to search for antioxidant materials obtained from dendrimer and characterizing products for the synthesis of polymer (including polysaccharide)-based fuel cells and skin scaffolds. In addition, it allows the characterization of polymeric nitric oxide release architectures and exploration of redox enzyme mechanisms. The instrument also serves researchers creating polymer/dendrimer-based materials.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器项目和化学研究仪器项目支持。中央密歇根大学正在购买一台配备自动样品加载器和温度控制系统的500 MHz核磁共振光谱仪，以支持本杰明·斯沃茨博士及其同事安雅·米勒、贾尼斯·托马西克、李春云和杜文军的研究。这种光谱仪允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究化学和生物相关的物种。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器是该机构化学和生物化学的本科生和研究生以及来自地区社区大学的合作者的教学、研究和研究培训的组成部分。授予核磁共振光谱仪的目的是加强各级的研究和教育。它尤其影响了碳水化合物/脂肪合成的研究，创造了研究细菌的化学工具，并产生了基于多糖的可再生材料。该仪器还用于寻找从树枝状大分子中获得的抗氧化材料，以及用于合成基于聚合物(包括多糖)的燃料电池和皮肤支架的表征产品。此外，它还可以表征聚合物一氧化氮的释放结构，并探索氧化还原酶的作用机制。该仪器还为创造聚合物/树枝状大分子材料的研究人员提供服务。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。