MRI: Acquisition of 500 MHz Nuclear Magnetic Resonance Spectrometer for Research and Education Infrastructure Enhancement at Michigan Technological University and Upper Peninsula

MRI：采购 500 MHz 核磁共振波谱仪，用于增强密歇根理工大学和上半岛的研究和教育基础设施

• 批准号: 2117318
• 负责人: Marina Tanasova
• 金额: $ 44.61万
• 依托单位: Michigan Technological University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2117318&HistoricalAwards=false
• 关键词: MRI; Acquisition; 500; MHz; Nuclear

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Michigan Technological University is acquiring a 500 MHz nuclear magnetic resonance (NMR) spectrometer to support the research of Marina Tanasova and colleagues Haiying Liu, Shiyue Fang, Evan Kane and Daisuke Minakata. This spectrometer allows research in a variety of fields including biological chemistry, organic synthesis, nucleotides, polymers, and environmental science. NMR spectroscopy is a powerful tool that chemists use for the elucidation of molecular structure. Unknown substances can be identified, specific arrangement of atoms in molecules can be determined, and the dynamics of interactions between molecules in solution or in the solid state can be studied. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as regionally.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially facilitates the exploration of substrate selection by facilitative sugar transporters gluts with diverse stable sugar mimics, the execution of solid-phase synthesis of monodisperse polyethylene glycol and its derivatives, and the development of technologies for the synthesis of sensitive oligodeoxynucleotides. The instrument is also used to support the design and development of conjugated polymers with xanthene units and three-emission conjugated polymers with xanthene units fused with dyes. In addition, it allows for the investigation of the photochemical fate of dissolved amino acids in natural aquatic environments, the understanding of soil carbon cycling via pore water-dissolved organic matter, and the study of electro-responsive underwater adhesive based on mussel adhesive.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划共同支持。密歇根理工大学正在购买一台500 MHz核磁共振（NMR）光谱仪，以支持Marina Tanasova及其同事Haiying Liu，Shiyue Fang，Evan Kane和Daisuke Minakata的研究。该光谱仪可用于生物化学、有机合成、核苷酸、聚合物和环境科学等多个领域的研究。核磁共振波谱是化学家用来阐明分子结构的有力工具。可以识别未知物质，可以确定分子中原子的特定排列，可以研究溶液或固态分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。该仪器是该机构以及区域化学和生物化学本科生和研究生教学、研究和研究培训的一个组成部分，授予NMR光谱仪的目的是加强各级的研究和教育。它特别有利于探索底物的选择，通过促进糖转运蛋白与各种稳定的糖模拟物，单分散聚乙二醇及其衍生物的固相合成的执行，以及敏感的寡脱氧核苷酸合成技术的发展。该仪器还用于支持含氧杂蒽单元的共轭聚合物和含氧杂蒽单元与染料融合的三发射共轭聚合物的设计和开发。此外，它允许调查自然水生环境中溶解氨基酸的光化学命运，通过孔隙水溶解有机物了解土壤碳循环，以及对电-该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查进行评估，被认为值得支持的搜索.