MRI: Acquisition of 500 MHz Nuclear Magnetic Resonance Spectrometer for Research and Education Infrastructure Enhancement at Michigan Technological University and Upper Peninsula

该奖项由主要研究仪器和化学研究仪器项目联合支持。密歇根理工大学正在购买一台500 MHz核磁共振（NMR）光谱仪，以支持Marina Tanasova及其同事刘海英、方士岳、Evan Kane和Daisuke Minakata的研究。该光谱仪允许在各种领域的研究，包括生物化学，有机合成，核苷酸，聚合物和环境科学。核磁共振光谱学是化学家用来阐明分子结构的有力工具。可以识别未知物质，可以确定分子中原子的具体排列，可以研究溶液或固体状态下分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。该仪器是该机构以及地区化学和生物化学本科生和研究生的教学、研究和研究训练的一个组成部分。核磁共振光谱仪的奖励旨在加强各级的研究和教育。它特别有助于探索通过各种稳定的糖模拟物的促进性糖转运体的底物选择，单分散聚乙二醇及其衍生物的固相合成的实施，以及合成敏感的寡脱氧核苷酸的技术的发展。该仪器还用于支持设计和开发含杂蒽的共轭聚合物和含杂蒽与染料融合的三发射共轭聚合物。此外，它还允许研究天然水生环境中溶解氨基酸的光化学命运，了解土壤碳通过孔隙水溶有机质循环，以及研究基于贻贝胶的电响应水下粘合剂。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Michigan Technological University is acquiring a 500 MHz nuclear magnetic resonance (NMR) spectrometer to support the research of Marina Tanasova and colleagues Haiying Liu, Shiyue Fang, Evan Kane and Daisuke Minakata. This spectrometer allows research in a variety of fields including biological chemistry, organic synthesis, nucleotides, polymers, and environmental science. NMR spectroscopy is a powerful tool that chemists use for the elucidation of molecular structure. Unknown substances can be identified, specific arrangement of atoms in molecules can be determined, and the dynamics of interactions between molecules in solution or in the solid state can be studied. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution as well as regionally.The award of the NMR spectrometer is aimed at enhancing research and education at all levels. It especially facilitates the exploration of substrate selection by facilitative sugar transporters gluts with diverse stable sugar mimics, the execution of solid-phase synthesis of monodisperse polyethylene glycol and its derivatives, and the development of technologies for the synthesis of sensitive oligodeoxynucleotides. The instrument is also used to support the design and development of conjugated polymers with xanthene units and three-emission conjugated polymers with xanthene units fused with dyes. In addition, it allows for the investigation of the photochemical fate of dissolved amino acids in natural aquatic environments, the understanding of soil carbon cycling via pore water-dissolved organic matter, and the study of electro-responsive underwater adhesive based on mussel adhesive.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.