From Seed to Seed: Genome-wide Expression Analysis of Arabidopsis throughout Its Life Cycle

从种子到种子：拟南芥整个生命周期的全基因组表达分析

• 批准号: 0117281
• 负责人: John Quackenbush
• 金额: $ 90万
• 依托单位: Institute for Genomic Research
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0117281&HistoricalAwards=false
• 关键词: Seed; Genome; wide; Expression; Analysis

Arabidopsis thaliana is a plant model organism that has become a major research tool for plantBiologists. A primary motivation for the sequencing of Arabidopsis was that it would serve as a reference for other plant genomes. For this to be realized the functions of a large number of unknown and hypothetical genes must be deduced and a cross-reference between genes in Arabidopsis and other plant species provided. Ultimately, the development of the data resources will lead to a better understanding of gene expressions and function in plants.Predicted genes will be amplified and used to construct a whole genome microarray that will be used to look at patterns of gene express through the plant life cycle. Expressions data can help provide both functional assignments for genes and used in identifying metabolic pathways. The data will be analyzed using a suite of clustering and pattern recognition tool. A number of databases will be combined and integrated to provide a web-based view of gene expression and identification in Arabidopsis.

拟南芥（Arabidopsis thaliana）是一种植物模式生物，已成为植物生物学家的主要研究工具.对拟南芥进行测序的主要动机是它将作为其他植物基因组的参考。为了实现这一点，必须推导出大量未知和假设基因的功能，并提供拟南芥和其他植物物种基因之间的交叉参考。最终，数据资源的开发将导致更好地了解植物中的基因表达和功能。预测的基因将被扩增并用于构建全基因组微阵列，该微阵列将用于观察植物生命周期中的基因表达模式。表达数据可以帮助提供基因的功能分配，并用于识别代谢途径。将使用一套聚类和模式识别工具分析数据。一些数据库将被合并和整合，以提供一个基于网络的观点的基因表达和识别拟南芥。