I/UCRC: BioMolecular Interaction Technology Center
I/UCRC: BioMolecular Interaction Technology Center
批准号:
0119825
负责人:
Thomas Laue
金额:
$35.0万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-09-01 至 2010-08-31
中文摘要
制药和生物技术产业在维持和促进人口健康方面发挥着至关重要的作用,是美国经济的主要组成部分。这些行业已经从疾病的经验性治疗演变为药物开发的复杂方法,这需要对生命过程的生物化学有更深的了解。因此,对生物分子相互作用的准确描述已经成为了解疾病机制的核心要素,现在也是设计安全有效的药物的关键因素。各种仪器和方法被用来表征生物分子间的相互作用。这一I/UCRC将使制药、生物技术和仪器公司能够共同努力,开发表征分子相互作用的先进技术。
英文摘要
The pharmaceutical and biotechnology industries play a vital role in maintaining and promoting a healthy population, and constitute a major sector of the US economy. These industries have evolved from the empirical treatment of disease to a sophisticated approach for drug development which requires a deeper understanding of the biochemistry of life processes. As a consequence, the accurate description of biomolecular interactions has become a central element in understanding disease mechanisms, and now is an essential ingredient for devising safe and effective pharmaceuticals. A variety of instruments and methods are used to characterize biomolecular interactions. This I/UCRC will enable pharmaceutical and biotechnological, and instrumentation companies to work together toward the development of advanced technologies for characterizing molecular interactions.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Biomolecular Interaction Technologies Center
-
批准号:0638467
-
项目类别:Continuing Grant
-
资助金额:$21.5万
-
财政年份:2006
-
负责人:Thomas Laue
-
依托单位:
Web-based Computer Aided Interpretation of Analytical Sedimentation Data
-
批准号:0330843
-
项目类别:Standard Grant
-
资助金额:$5.0万
-
财政年份:2003
-
负责人:Thomas Laue
-
依托单位:
Analytical Ultracentrifugation as a Method for Identifying and Characterizing Src-Containing Multi-Protein Complexes in Cancer Cells
-
批准号:0226188
-
项目类别:Standard Grant
-
资助金额:$2.5万
-
财政年份:2002
-
负责人:Thomas Laue
-
依托单位:
Gordon Research Conference on Reversible Association in Structural and Molecular Biology to be held Jan. 30 - Feb. 4, 2000 in Ventura, California
-
批准号:9980450
-
项目类别:Standard Grant
-
资助金额:$0.6万
-
财政年份:2000
-
负责人:Thomas Laue
-
依托单位:
Planning Grant for BioMolecular Interaction Technology Center
-
批准号:0002962
-
项目类别:Standard Grant
-
资助金额:$1.0万
-
财政年份:2000
-
负责人:Thomas Laue
-
依托单位:
Innovative Technologies for Analytical Ultracentrifugation
-
批准号:9876582
-
项目类别:Continuing Grant
-
资助金额:$100.0万
-
财政年份:1999
-
负责人:Thomas Laue
-
依托单位:
Determination of Charge-Structure Relationships for DNA
-
批准号:9807550
-
项目类别:Continuing Grant
-
资助金额:$18.0万
-
财政年份:1998
-
负责人:Thomas Laue
-
依托单位:
Instruments and Methods for Determining the Role of Charge in Macromolecular Structure and Assembly
-
批准号:9314040
-
项目类别:Continuing Grant
-
资助金额:$130.15万
-
财政年份:1994
-
负责人:Thomas Laue
-
依托单位:
Development of Devices and Methodology for the Direct Determination of Macromolecular Charge
-
批准号:8914571
-
项目类别:Standard Grant
-
资助金额:$45.57万
-
财政年份:1990
-
负责人:Thomas Laue
-
依托单位:
Development of Modern Analytical Centrifugation Instruments and Methods
-
批准号:9002027
-
项目类别:Continuing Grant
-
资助金额:$57.91万
-
财政年份:1990
-
负责人:Thomas Laue
-
依托单位:
Development of Real-Time Acquisition and Analysis Capabilities for the Refractometric Optical System of the Analytical Ultracentrifuge
-
批准号:8615815
-
项目类别:Continuing Grant
-
资助金额:$43.17万
-
财政年份:1987
-
负责人:Thomas Laue
-
依托单位:
Conference on the Future of Analytical Ultracentrifugation, San Francisco, California, February 9, 1986
-
批准号:8605201
-
项目类别:Standard Grant
-
资助金额:$0.12万
-
财政年份:1986
-
负责人:Thomas Laue
-
依托单位:
海外基金