课题基金 / 基金详情

2001 Technology for a Sustainable Environment: NSF/EPA Partnership: Metabolic Engineering of Monooxygenases for 1-Naphthol and Styrene Epoxide Formation (TSE01-D)

2001 Technology for a Sustainable Environment: NSF/EPA Partnership: Metabolic Engineering of Monooxygenases for 1-Naphthol and Styrene Epoxide Formation (TSE01-D)
2001 年可持续环境技术:NSF/EPA 合作伙伴关系:1-萘酚和苯乙烯环氧化物形成的单加氧酶代谢工程 (TSE01-D)
批准号:
0124401
负责人:
Thomas Wood
金额:
$69.01万
依托单位:
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-02-01 至 2006-02-28

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中文摘要
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英文摘要
0124401WoodThe objective of this project is to optimize the activity and expression of monooxygenases for the purpose of converting naphthalene to 1-naphthol and (chiral) styrene epoxide. Replacing the current method for producing 1-naphthol and styrene epoxide with the proposed enzymatic alternative may prove to be more environmentally benign in that less solvent and by-product wastes will result. There are two components to the work: (1) enzyme "breeding" (University of Connecticut) and (2) regulation of expression and bioprocess optimization (University of Maryland), which are highly synergistic.
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