New Hydrogen Bonding Modules for Supramolecular Polymer Chemistry

用于超分子聚合物化学的新型氢键模块

• 批准号: 0212772
• 负责人: Steven Zimmerman
• 金额: --
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0212772&HistoricalAwards=false
• 关键词: New; Hydrogen; Bonding; Modules; Supramolecular

The objectives of this work are to develop DNA base-pair analogs which can self assemble (using hydrogen bonding) into oligomers and polymers that adopt defined three dimensional structures. They will start this investigation by preparing new base-pair analogs and study the structural factors that determine base-pair stability. They will also work to develop a model to predict analog base-pair stability. Oligomers and polymers of these base pair analogs will then be synthesized with the goal being the preparation of self assembled polymers which can equilibrate between folded and sheet-like structures. Molecules which can use light to accomplish this equilibration are particularly desirable and will be studied in detail. These self assembling polymeric materials may have properties, such as self healing, which are not currently available with traditional covalently bonded polymers. The incorporation of these small molecules with defined hydrogen bonding capabilities into bulk commerical polymers may one day lead to higher performance materials.With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Steven C. Zimmerman of the Department of Chemistry at the University of Illinois. Dr. Zimmerman and his students will work on the development of DNA base-pair analogs which can self assemble into oligomers and polymers that adopt defined three dimensional structures. Polymers of these base-pair analogs will then be prepared with the goal being the preparation of self assembled polymers which can equilibrate between folded and sheet-like structures. Molecules which can use light to accomplish this equilibration are particularly desirable and will be studied in detail. These self assembling polymeric materials may have properties, such as self healing, which are not currently available with traditional covalently bonded polymers. The incorporation of these small molecules with defined hydrogen bonding capabilities into bulk commerical polymers may one day lead to higher performance materials. Students trained during the course of this interdisciplinary work will gain skills needed by the pharmaceutical, polymer and speciality chemicals industries.

这项工作的目标是开发DNA碱基对类似物，它可以自组装（使用氢键）成低聚物和聚合物，采用明确的三维结构。他们将从制备新的碱基对类似物开始研究，并研究决定碱基对稳定性的结构因素。他们还将开发一个模型来预测模拟碱基对的稳定性。然后将合成这些碱基对类似物的低聚物和聚合物，其目标是制备能够在折叠和片状结构之间平衡的自组装聚合物。能够利用光来实现这种平衡的分子是特别需要的，并将被详细研究。这些自组装聚合物材料可能具有自修复等特性，而这些特性是目前传统共价键聚合物所不具备的。将这些具有确定氢键能力的小分子结合到大宗商用聚合物中，可能有一天会产生更高性能的材料。有了这个奖项，有机和大分子化学项目支持了伊利诺伊大学化学系Steven C. Zimmerman博士的研究。齐默尔曼博士和他的学生将致力于开发DNA碱基对类似物，这种类似物可以自组装成低聚物和聚合物，采用明确的三维结构。然后将制备这些碱基对类似物的聚合物，其目标是制备可在折叠和片状结构之间平衡的自组装聚合物。能够利用光来实现这种平衡的分子是特别需要的，并将被详细研究。这些自组装聚合物材料可能具有自修复等特性，而这些特性是目前传统共价键聚合物所不具备的。将这些具有确定氢键能力的小分子结合到大宗商用聚合物中，可能有一天会产生更高性能的材料。在这个跨学科的工作过程中训练的学生将获得制药，聚合物和特种化学品行业所需的技能。