Integrated Sensing: High-speed 3D Microscopy by Hybrid Optical-Digital Encoding and Processing

本提案的目标是开发一种新的范例，高速，三维（3D）图像场景采集和渲染。该项目特别针对在视频速率下的3D动态微观场景成像，可以进一步以可变的速度和从多个视角与立体显示系统离线可视化。到目前为止，没有其他技术可以同时提供所提出的系统的高时间和三维空间分辨率。这种新型显微镜有望同时获得包含大景深、高分辨率和3D范围信息的图像。光学-数字系统基于一种新的方法，其中a）光学部分，B）数字计算部分，和c）渲染部分同时设计。 该显微镜将联合收割机，第一次，旋转点扩散函数和波前编码技术。该系统将面向表面浮雕applications非常快的动态过程影响微观3D场景。特别是，它将被测试用于MEMS检测。该系统将在先进制造、远程显微信息共享、生物成像和其他需要以非常高的速度获取和可视化3D微型场景映射的应用中具有极其重要的价值。研究生和本科生将积极参与分析、设计和实验。所开发的仪器将在以后的几年中用于显微镜可视化领域的教育。

The goal of this proposal is to develop a novel paradigm for high-speed,three-dimensional (3D) image scene acquisition and rendering. This projectis especially directed at imaging 3D dynamic microscopic scenes at videorates that can be further visualized off-line at variable speeds and frommultiple viewpoints with stereoscopic display systems. As of today, noother technique can offer simultaneously the high temporal and 3D-spatialresolution of the proposed system. The new microscope is expected toacquire images simultaneously containing large depth of field, highresolution, and 3D-range information.The optical-digital system is based on a novel approach in which a) theoptical, b) the digital computational, and c) the rendering parts of thesystem are simultaneously designed. The microscope will combine, for thefirst time, the rotating point-spread-function and the wavefront codingtechnologies. The system will be oriented to surface relief applicationswhere very fast dynamical processes affect the microscopic 3D scene. Inparticular, it will be tested for MEMS inspection.The proposed system will be extremely valuable in micro-nano patternrecognition and inspection for advanced manufacturing, remote microscopicinformation sharing, biological imaging, and other applications thatrequire the acquisition and visualization of 3D miniature scene-mappingsat very high speeds.Graduate and undergraduate students will be actively involved in theanalysis, design, and experiments. The instrumentation developed will beavailable for education in the area of microscopic visualization insubsequent years.