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ITR/NGS: A Framework for Discovery, Exploration and Analysis of Evolutionary Simulation Data (DEAS)

ITR/NGS: A Framework for Discovery, Exploration and Analysis of Evolutionary Simulation Data (DEAS)
ITR/NGS:进化模拟数据发现、探索和分析的框架 (DEAS)
批准号:
0326386
负责人:
Raghu Machiraju
金额:
$80.06万
依托单位国家:
美国
项目类别:
Continuing Grant
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-09-15 至 2008-08-31

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中文摘要
翻译
在科学领域,挑战总是在噪音中寻找信号。例子包括飓风预报和监测情报和地震活动。我们的建议通过一个广泛的框架来解决这些问题,我们称之为广义特征挖掘。该框架有两个主要组成部分:特征挖掘和基于形状的数据挖掘和分析。在其核心,特征挖掘检测特定应用程序域的特征。每个实例都涉及为其量身定做的特定扩展形状描述。对于进化模拟,特征挖掘还可以跟踪多个时间尺度上的特征。基于形状的数据挖掘和分析从这个过程中吸取了教训。其目的是将来自扩展形状描述符的信息与瞬变检测相关联,以发现或改进特征演化的时空规则。环境影响,如墙,必须内置到规则中,以便它们是可预测的。为了闭合循环,可以在发现或改进检测到的要素时显示它们。我们的框架预测的进化规则可以导致新的科学{不仅理解潜在的现象,而且还导致封装本质的计算更简单的模型。
英文摘要
In science the challenge is always finding a signal in the noise. Examples include hurricane forecasting and monitoring both intelligence and seismic activity. Our proposal addresses these issues through a broad framework we call generalized feature mining. The framework has two major components: feature mining, and shape-based data mining and analysis. At its core, feature mining detects features for a specific application domain. Each instance involves a specific extended shape description tailored to it. For evolutionary simulations, feature mining also tracks features across multiple temporal scales. Shape-based data mining and analysis learn from the process. The aim is to correlate information from the extended shape descriptors with transient detection to find or refine spatio-temporal rules for the evolution of features. Environmental influences, such as walls, must be built into the rules so they are predictive.To close the loop, the detected features can be displayed as they are found or refined. The evolutionary rules predicted by our framework can lead to new science { not only understanding the underlying phenomena but also leading to computationally simpler models that encapsulate the essentials.
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Collaborative Research: Autonomous Computing Materials
  • 批准号:
    1940168
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $35.66万
  • 财政年份:
    2019
  • 负责人:
    Raghu Machiraju
  • 依托单位:
Spokes: MEDIUM: MIDWEST: Collaborative: Community-Driven Data Engineering for Substance Abuse Prevention in the Rural Midwest
  • 批准号:
    1761969
  • 项目类别:
    Standard Grant
  • 资助金额:
    $65.1万
  • 财政年份:
    2018
  • 负责人:
    Raghu Machiraju
  • 依托单位:
SCC-Planning: Using Innovations in Big Data and Technology to Address the High Rate of Infant Mortality in Greater Columbus Ohio
  • 批准号:
    1737560
  • 项目类别:
    Standard Grant
  • 资助金额:
    $10.0万
  • 财政年份:
    2017
  • 负责人:
    Raghu Machiraju
  • 依托单位:
BCSP: ABI Innovation: Collaborative Research: Predicting changes in protein activity from changes in sequence by identifying the underlying Biophysical Conditional Random Field
  • 批准号:
    1262469
  • 项目类别:
    Standard Grant
  • 资助金额:
    $41.14万
  • 财政年份:
    2014
  • 负责人:
    Raghu Machiraju
  • 依托单位:
国内基金
海外基金
NGS结合免疫微环境预测肝癌经动脉灌注化疗栓塞(TACE)联合靶免治疗疗效的研究
基于NGS的HIV分型及耐药基因检测的多中心临床验证
  • 批准号:
    2023JJ60396
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2023
  • 负责人:
    郑芳
  • 依托单位:
NGS-MHs 分型体系在肿瘤组织个体识别鉴定中的应用探索
Alport 综合征新致病基因突变和表观组学的研究及建立以靶向NGS 技术为基础的基因诊断体系
  • 批准号:
    2021JJ70111
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    石大志
  • 依托单位: