Acquisition of a High-Resolution Mass Spectrometer

购置高分辨率质谱仪

• 批准号: 0443618
• 负责人: Jonathan Lee
• 金额: $ 18.42万
• 依托单位: Trustees of Boston University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0443618&HistoricalAwards=false
• 关键词: Acquisition; Resolution; Mass; Spectrometer

With support from the Chemistry Research Instrumentation and Facilities - Multiuser Instrument Acquisition (CRIF-MU) Program, the Department of Chemistry at Boston University will purchase a liquid chromatograph/mass spectrometer (LC/MS) time of flight (TOF) system. This equipment will enhance research in a number of areas including 1) the preparation and evaluation of dendritic-linear hybrid macromolecules; 2) asymmetric synthesis using (E)-crotylsilane reagents; 3) the development of new methodologies for chemical synthesis of complex molecules; 4) synthesis of natural products using catalytic methodologies as a source of selective organic transformations; and 5) homo Diels-Alder chemistry. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. It is one of the fastest growing and most widely used analytical instrumentation techniques. Because of this, it is important for undergraduate and graduate students to be exposed to the technique. Graduate students, undergraduate summer and postdocs will use this instrument for their research.

在化学研究仪器和设施-多用户仪器采购（CRIF-MU）计划的支持下，波士顿大学化学系将购买液相色谱/质谱仪（LC/MS）飞行时间（TOF）系统。该设备将加强若干领域的研究，包括：1）树枝状-线性混合高分子的制备和评价; 2）使用（E）-巴豆基硅烷试剂的不对称合成; 3）复杂分子化学合成新方法的开发; 4）使用催化方法作为选择性有机转化的来源合成天然产品; 5）homo Diels-Alder化学。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。 它是发展最快、使用最广泛的分析仪器技术之一。 因此，本科生和研究生接触这项技术是很重要的。 研究生，本科生暑期和博士后将使用此仪器进行研究。