Genes Patterning the Arabidopsis Fruit

拟南芥果实的基因模式

• 批准号: 0515966
• 负责人: Martin Yanofsky
• 金额: $ 59.5万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0515966&HistoricalAwards=false
• 关键词: Genes; Patterning; Arabidopsis; Fruit

Fruits play a central role in agriculture since they are the harvested product for many plant species. It is likely that the functional understanding of fruit development genes in the model plant system of Arabidopsis will be directly transferable to crop plants, and thus this research should facilitate gene discovery in plants of agricultural importance. Fruit size, shape, and method of seed dispersal varies markedly in different species, but the molecular and genetic basis of this diversity is completely unknown. The central issue addressed involves the identification of the major genes that are required for normal fruit development. A number of genes that control the formation of the different parts of the fruit will be identified and these genes are important for fruit size, shape and seed dispersal. A series of genetic and molecular approaches are proposed to identify and characterize additional genes that regulate the upstream patterning processes that control fruit development. These studies should lead to a simple model for the action of major genes in controlling fruit development and this model should be generally applicable to many species. This research will also provide excellent training opportunities for students and postdoctoral fellows. The resources created will be incorporated into laboratory courses and outreach efforts.

水果在农业中起着核心作用，因为它们是许多植物物种的收获产品。 拟南芥模式植物系统中果实发育基因的功能理解很可能直接转移到作物中，因此这项研究应该有助于农业重要植物中基因的发现。 果实的大小、形状和种子传播的方式在不同的物种中有显著的差异，但是这种多样性的分子和遗传基础是完全未知的。 解决的中心问题涉及到确定的主要基因是正常的水果发育所需的。控制果实不同部分形成的许多基因将被鉴定出来，这些基因对果实的大小、形状和种子传播都很重要。 提出了一系列的遗传和分子的方法来确定和表征额外的基因，调节上游模式的过程，控制果实发育。 这些研究应导致一个简单的模式，在控制果实发育的主基因的行动，这一模式应普遍适用于许多物种。 这项研究还将为学生和博士后研究员提供极好的培训机会。所创造的资源将纳入实验室课程和外联工作。