Multi-photon imaging for infection, immunity, and self recognition

用于感染、免疫和自我识别的多光子成像

• 批准号: LE0989226
• 负责人: Prof William Heath
• 金额: $ 22.67万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0989226
• 关键词: Multi; photon; imaging; infection; immunity

This proposal will address a gap in our imaging capabilities, allowing us to visualise the movement of immune cells and infectious agents such as bacteria and viruses within living tissues. This will immensely improve our capacity to understand interactions between the immune system, invading organisms and the rest of our body. The intravital imaging system will provide novel insights into how the immune system works, which will benefit the design of vaccines, the treatment of cancer, and our understanding of allergy. This state-of-the-art facility will also provide vital training in an emerging technology that will have application in many areas of biology.

该提案将解决我们成像能力的差距，使我们能够可视化免疫细胞和感染因子（如细菌和病毒）在活组织中的运动。这将极大地提高我们理解免疫系统、入侵生物和我们身体其他部分之间相互作用的能力。活体成像系统将为免疫系统如何工作提供新的见解，这将有利于疫苗的设计，癌症的治疗以及我们对过敏的理解。这个最先进的设施还将提供一项新兴技术的重要培训，该技术将在生物学的许多领域得到应用。