Acquisition of a Single Crystal X-ray Diffractometer

在主要研究仪器（MRI）项目的支持下，加州大学圣克鲁兹分校化学系将获得一台带有CCD探测器和低温能力的单晶x射线衍射仪。通过仔细分析详细的结构化学数据，主要用户将研究以下系统：a)阴离子基应用的阳离子微孔和层状金属氧化物；B)金属离子在生物学中的作用；C)海洋海绵衍生产品的化学生物学；D)生物学上重要配体的电荷密度研究；e)铜在朊病毒蛋白中的结合。x射线衍射仪可以精确测量分子的完整三维结构，包括键的距离和角度，并提供分子相对于邻近分子的空间排列的准确信息。这些研究将在许多领域产生影响，特别是材料化学和生物化学。

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at the University of California in Santa Cruz will acquire a single-crystal X-ray diffractometer with CCD detector and low temperature capability. By careful analyses of detailed structural chemical data, made possible by the enhanced capabilities of the new instrument, the major users will investigate the following systems: a) cationic microporous and layered metal oxides for anion-based applications; b) the role of metal ions in biology; c) chemical biology of marine sponge-derived products; d) charge density studies of biologically important ligands; and e) copper binding in the prion protein. The X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of the molecule relative to the neighboring molecules. These studies will have an impact in a number of areas, especially materials chemistry and biochemistry.