Collaborative Workshop on Bio-Nano Manufacturing for Cellular Engineering; March, 2007; NIST, Gaithersburg, Maryland

本次合作研讨会的目的是将生物制造和纳米制造新兴领域的研究人员聚集在一起，探索生物和纳米制造界面的协同作用和机会。纳米工艺技术的例子包括表面改性、纳米操作、热、电和光学加工和纳米级沉积、静电纺丝、纳米级组件的合成和结合以及利用生物生命来制造纳米材料。研讨会将确定、讨论和推荐生物纳米制造可能的合作领域。它将邀请和吸引来自生物纳米制造学科领域的专家，如基于自由形状制造的生物制造，生物打印和图案，器官和细胞打印，生物材料设计和涂层，以及纳米设计和多尺度建模，主动和被动纳米结构的设计，功能分级的层次纳米集成系统，细胞感觉和执行器系统，多功能纳米和微计量工具，靶向药物递送，等。此外，研讨会还将讨论培训下一代劳动力的教育课程的新机遇。工业成员将是这个研讨会的重要组成部分，在这个研讨会上，小型和大型工业的进展将被讨论和建议，以确保美国工业在生物纳米制造这一新兴领域的全球竞争力。随着生物制造和纳米级制造并行出现，越来越明显的是，它们的交叉点是新发现和发明存在的关键途径，而工程纳米级结构、图案工具和计量手段可以有效地应用于细胞工程水平的可预测、可生产/可复制和生产性2D和3D生物制造。本次研讨会将为纳米制造提供必要的见解，以领导二维和三维主动和被动纳米结构，自定向组装，纳米尺度图案，二维和三维分层细胞和分子打印和集成，以及多功能计量学的研究。

The objective of this collaborative workshop is to bring together researchers in the emerging fields of biomanufacturing and nanomanufacturing to explore synergies and opportunities at the interface of bio and nano manufacturing. Examples of nano-process techniques include surface modification, nanomanipulation, thermal, electrical and optical machining and deposition at nanoscale, electrospinning, synthesis and incorporation of nanoscale components and usage of biological life for the creation of nanomaterials. The workshop will identify, discuss and recommend possible collaborative areas for bio-nano manufacturing. It will invite and engage experts from the range of bio-nano manufacturing subjects areas such asfreeform fabrication based biomanufacturing, bio-printing and patterning, organ and cell printing, biomaterials designing and coating as well as nanodesigning and multiscale modeling, active and passive nano structures by designing, functionally graded hirachical nanointegrated systems, cellular sensory and actuator systems, multifunctional nano and micro metrology tools, targeted drug delivery, etc. In addition, this workshop will also discuss new opportunities for education curricula to train next generation workforce. Industry members will be an important part of this workshop where progress in small and well as large industries will be discussed and recommended to assure global competitivenss of US industries in this emerging field of bio-nano manufacturing.As biological manufacturing and nanoscale manufacturing emerges parallel, it is becoming increasing evident that their intersections are critical pathways where new discoveries and inventions reside and where engineered nano scale structures, patterning tools and metrology means can be effectively applied for predictable, producible/reproducible, and productive 2D and 3D biomanufacturing at cellular engineering level. This workshop will provide nanomanufacturing the insight necessary to lead research with 2D and 3D active and passive nanostructures, self- and directed- assemblies, nanoscale patterning, 2D and 3D hierarchical cell and molecule printing and integration, and multifucntional metrology.