Collaborative Workshop on Bio-Nano Manufacturing for Cellular Engineering; March, 2007; NIST, Gaithersburg, Maryland

这次合作研讨会的目的是将新兴的生物制造和纳米制造领域的研究人员聚集在一起，探索生物和纳米制造交界处的协同效应和机会。纳米加工技术的例子包括表面改性、纳米操纵、纳米级的热、电和光学加工和沉积、静电纺丝、纳米级部件的合成和并入以及利用生物生命创造纳米材料。研讨会将确定、讨论和推荐生物纳米制造的可能合作领域。它将邀请和聘请来自生物纳米制造学科领域的专家，如基于自由形式制造的生物制造、生物印刷和图案化、器官和细胞印刷、生物材料设计和涂层以及纳米设计和多尺度建模、通过设计的主动和被动纳米结构、功能分级的水生纳米集成系统、细胞传感和致动器系统、多功能纳米和微型计量工具、靶向药物输送等。此外，工作坊还将讨论教育课程培训下一代劳动力的新机会。行业成员将是这次研讨会的重要组成部分，会上将讨论和建议小型和大型工业的进展，以确保美国工业在这一新兴的生物纳米制造领域的全球竞争力。随着生物制造和纳米制造并行出现，越来越明显的是，它们的交叉是新发现和发明的关键途径，工程纳米结构、图案化工具和计量手段可以有效地应用于细胞工程水平的可预测、可生产/可重现和生产性的2D和3D生物制造。该研讨会将提供领导研究所需的纳米制造洞察力，包括2D和3D主动和被动纳米结构、自组装和定向组装、纳米级图案、2D和3D分级细胞和分子打印和集成，以及多功能计量学。

The objective of this collaborative workshop is to bring together researchers in the emerging fields of biomanufacturing and nanomanufacturing to explore synergies and opportunities at the interface of bio and nano manufacturing. Examples of nano-process techniques include surface modification, nanomanipulation, thermal, electrical and optical machining and deposition at nanoscale, electrospinning, synthesis and incorporation of nanoscale components and usage of biological life for the creation of nanomaterials. The workshop will identify, discuss and recommend possible collaborative areas for bio-nano manufacturing. It will invite and engage experts from the range of bio-nano manufacturing subjects areas such asfreeform fabrication based biomanufacturing, bio-printing and patterning, organ and cell printing, biomaterials designing and coating as well as nanodesigning and multiscale modeling, active and passive nano structures by designing, functionally graded hirachical nanointegrated systems, cellular sensory and actuator systems, multifunctional nano and micro metrology tools, targeted drug delivery, etc. In addition, this workshop will also discuss new opportunities for education curricula to train next generation workforce. Industry members will be an important part of this workshop where progress in small and well as large industries will be discussed and recommended to assure global competitivenss of US industries in this emerging field of bio-nano manufacturing.As biological manufacturing and nanoscale manufacturing emerges parallel, it is becoming increasing evident that their intersections are critical pathways where new discoveries and inventions reside and where engineered nano scale structures, patterning tools and metrology means can be effectively applied for predictable, producible/reproducible, and productive 2D and 3D biomanufacturing at cellular engineering level. This workshop will provide nanomanufacturing the insight necessary to lead research with 2D and 3D active and passive nanostructures, self- and directed- assemblies, nanoscale patterning, 2D and 3D hierarchical cell and molecule printing and integration, and multifucntional metrology.